Award Data

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project will focus on the design of the first completely automated radio frequency ablation (RFA) system for breast tissue. Of the approximately 200,000 breast cancer patients in the US who elect lumpectomy annually, over 20% must undergo re-operation due to lack of clear margins. Furthermore, many b ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is to establish a broadly applicable, breakthrough biocatalytic technology to produce an important class of compounds called chiral cyclopropanes. Cyclopropanes are key intermediates that are used in the synthesis of drugs, crop protection agents, and high-value electronic chemicals. Products accessib ...

The broader impact and commercial potential of this Small Business Innovation Research (SBIR) Phase II project is to treat chronic back and lower limb pain more effectively using a high-resolution stimulation technology. Lower back pain affects more than 100M Americans. While spinal cord neuro-modulation is successful for about 60% of patients, many people remain untreated and suffer from chronic ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project will be the development of software and monitoring system for the conservation of water resources and the economic sustainability of agricultural crop producers. Agricultural production uses a great deal of water. In California alone, 80% percent of all water usage goes to agriculture. As com ...

The broader impact/commercial potential of this project is that it addresses the bandwidth crisis, the problem of transmitting an exponentially growing amount of data through a fixed amount of increasingly congested spectrum. The bandwidth crisis limits economic growth by constraining communication, and also poses very serious challenges for national defense and disaster response. Making better us ...

The broader impact/commercial potential of this project relates to the development of non-pharmacological interventions capable of improving clinical outcomes following spinal fusion surgery. Between 1998 and 2008, the annual number of spinal fusion surgeries increased 137% from 174,223 to 413,171 and the national bill for spinal fusion increased 7.9-fold. The greatest risk in spinal fusion proced ...

This Small Business Innovation Research (SBIR) Phase II project will demonstrate compatibility of a novel polytetrafluoroethylene (PTFE) composite coating with metal-polymer bearings currently on the market, scale up the coating deposition process, and implement pilot processing lines. Currently, there is a need for a method to improve adhesion at the PTFE/metal interface while also reducing corro ...

This Small Business Innovation Research (SBIR) Phase II project will advance a novel probe-based direct transfer (PBDT) printing technology for manufacturing flexible hybrid electronic (FHE) devices. PBDT promises to deliver unprecedented selective, high-fidelity component transfer of a broad range of low-dimensional, high-performance electronic components with diverse architectures and sizes to f ...

The broader impact/commercial potential of this Small Business Technology Transfer Research (STTR) Phase II project stems from addressing the problem of embedded energy in the manufacture of magnesium metal for use in vehicle light-weighting. Improving fuel economy by incorporation of the lightest structural metal, magnesium, does not save on total lifecycle energy consumed if the magnesium was pr ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project will be the development and demonstration of a new manufacturing technology for lightweight bio-based plastics. Plastic produced from plant materials can have lower environmental impact than petroleum-based plastics, but price and performance issues have limited their adoption. In Phase I, Grow Plasti ...