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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Supercritical carbon dioxide for drying and sterilizing parenteral dosage forms

    SBC: SCF TECHNOLOGIES, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The long range goal of this project is to develop methods of using supercritical carbon dioxide (scCO2) to achieve terminal sterilization that meets or exceeds the USP standard of 10-6 microbial survival probability and that produces a dry drug product in a single process. The objective of this application is to identify at least one set of conditions in which ...

    SBIR Phase I 2009 Department of Health and Human Services
  2. ENCAPSULATED TRANSFECTED CELLS AS A THERAPY FOR MS

    SBC: Cytotherapeutics, Inc.            Topic: N/A

    N/A

    STTR Phase I 1998 Department of Health and Human Services
  3. Development of an Internet-Based Headache Management System for Teens

    SBC: RELIVE FOR KIDS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Chronic headache represent one of the most common and disabling medical conditions affecting adolescents, with a sizeable proportion of those affected continuing to have significant impairment into their adult years. Many of these children must exclusively rely on suboptimal medical treatments that in some cases can worsen headache conditions due to limited acc ...

    SBIR Phase I 2009 Department of Health and Human Services
  4. COMMUNITY BUILDING STRATEGIES FOR INCLUSIVE CLASSROOMS

    SBC: EDGE ENTERPRISES, INC.            Topic: N/A

    N/A

    SBIR Phase II 1998 Department of Health and Human Services
  5. Paragraph and Essay Writing Instruction for Struggling Secondary Writers

    SBC: EDGE ENTERPRISES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The purpose of this fast-track SBIR project entitled Paragraph and Essay Writing Instruction for Struggling Secondary Writers is to develop and evaluate the effectiveness of a total of four interactive multimedia (IM) software programs to be used to teach complex writing skills to struggling writers in secondary schools. The foci of the four programs will be ...

    SBIR Phase I 2009 Department of Health and Human Services
  6. An Intelligent Online System for Enhanced Recruitment of Patients for Clinical Re

    SBC: MIDWEST PSYCHIATRIC RESEARCH GROUP, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Recruitment and retention of subjects for clinical research is currently an inefficient and time-consuming process in the new drug development industry. This is especially true for the vulnerable populations of individuals with psychiatric disorders. This SBIR Phase I application will develop a prototype for recruitment enhancement with a novel internet- based ...

    SBIR Phase I 2009 Department of Health and Human Services
  7. High Content Screening for Muscular Dystrophy

    SBC: MYOMICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Duchenne Muscular Dystrophic (DMD) is a fatal genetic disease affecting tens of thousands of boys in the U.S. There is currently no cure for the disease and few drugs are available to slow the progressive loss in skeletal muscle strength. Glucocorticoids such as prednisone are one of the few classes of drugs in clinical use in DMD to slow the loss of muscle fu ...

    SBIR Phase II 2009 Department of Health and Human Services
  8. Interfacing of Research Modalities in Developmental Cognitive Neuroscience

    SBC: Perception Research Systems Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Biobehavioral research in a range of basic and translational disciplines (particularly cognitive neuroscience, neuropsychology and experimental psychology) increasingly involves the integration of multiple devices for the collection of data, such as EEG, fMRI, eye-tracking and physiological measurements (galvanic skin response, EKG). Current state-of-the-art ex ...

    STTR Phase II 2009 Department of Health and Human Services
  9. A self-contained wireless modular separation based sensor system

    SBC: Pinnacle Technology, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Recent advances have shown effective neurotransmitter analysis using capillary electrophoresis (CE). In a CE system, analyte is drawn through a narrow channel using ion movement resulting in an electroosmotic flow (EOF) generated by a high voltage electric field. Most microchip CE methods reported in the literature use the same separation and detection method f ...

    SBIR Phase I 2009 Department of Health and Human Services
  10. Automated sleep detection and deprivation in the fruit fly Drosophila melanogaste

    SBC: Pinnacle Technology, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Within the last seven years, Drosophila melanogaster or common fruit fly has been shown to be an invertebrate animal model for exploring genetic and proteomic mechanisms underlying sleep. While a great deal of progress has been made in the field of Drosophila sleep research using available tools, there currently exists no instrument designed specifically for th ...

    SBIR Phase I 2009 Department of Health and Human Services

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