Award Data

Attollo Engineering proposes to address the need for a quick-draw, pouch-storable laser rangefinder for day and night urban use. This self-contained unit will weigh less than 18 ounces and have a total volume less than 64 cubic inches. The system will provide post-fire target assurance, showing the operator where the laser landed on the target. In Phase I Attollo will survey and evaluate all relev ...

Project Summary According to the American Diabetes Association, Type 2 diabetes mellitus (T2D) affects at least 30 million Americans and is a major unmet public health concern with an annual cost in the United States of over $300 billion dollars. Additionally, nearly 25% of the U.S. population is already considered prediabetic, or at high risk of developing T2D. These individuals are characterized ...

ABSTRACT This project is the development of a non-invasively extending distal femur replacement (DFR) for children and adolescents subsequent to bone tumor resection. Each year in the US there are 200-250 malignant bone tumor diagnoses in the distal femurs of patients 15 years and younger. With advances in chemotherapy, limb salvage surgery utilizing a megaprosthesis has increasingly become the tr ...

The DLA has a need to identify competent and qualified domestic suppliers for mission-critical items that are becoming increasingly scarce. To combat the obsolescence issue, Mentis Sciences Inc. (Mentis) proposes a qualification effort for Bleed Air Ducting for the C-5 Galaxy Air Vehicle (C-5). Mentis understands the importance of supporting the C-5 and maintaining a strong supply chain for compon ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is improved access to state-of-the-art molecular diagnostic technologies in areas of significant unmet clinical need, such as women’s health. During the NSF I-Corps Program, the team identified urinary tract infections (UTIs) as pressing problem due to the currently lengthy clinical workflo ...

SUMMARY Amyotrophic lateral sclerosis (ALS) patients develop fatal paralysis as a result of progressive motor neuron loss in the brain and spinal cord. There are more than 5,000 new cases of ALS per year in the United States, with typical age of onset between 40 and 70 years of age. While SOD1 is a cytoplasmic protein, misfolded SOD1 can be secreted and form extracellular oligomers and aggregates. ...

PROJECT SUMMARY/ABSTRACT Clinical Need: The coming decades promise a revolution in the personalized treatment for patients with breast cancer, including approaches to minimize collateral damage of curative. However, to help facilitate this, the academic and industrial clinical research communities need improved diagnostic biomarkers to assess the presence of muscle diseases such as sarcopenia. Onc ...

Light Steering Technologies, Inc have developed and patented a novel mechanism for piston-tip-tilt platform actuation based on the laterally unconstrainted magnetic joint. This mechanism provides a typical ±20 degrees of platform motion and in optical applications, where the platform is a front surface mirror, offers scanning, pointing, tracking, and line-of-sight stabilization capabilities with ...

The broader impact of this Small Business Innovation Research (SBIR) Phase I project is to test an innovative new approach to generating industrially valuable microorganisms. If successful, the new approach will be demonstrated by improving the ability of an engineered bacterium to convert components of biomass into fuel. The benefit of that research will be to help develop a technology that can c ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is a novel hearing protection device which reduces the societal cost of noise induced hearing loss. Noise induced hearing loss is the one of the most prevalent occupational injuries in both US industry and the military, affecting more than 10 million workers at a total preventable economic cos ...