Award Data

"The objective of this project is to develop and validate a 2nd generation crack-growth prediction methodology for cold-worked fastener holes. The methodology will be based on a three-dimensional weight function, and will handle cracks growing from theedge of the hole, as well as cracks initiating in the residual tension zone away from the hole. A predictive capability, based on probabilistic fa ...

"As electronic devices continue to increase their functionality while continually decreasing their size, the need for smaller components becomes increasingly more important. Capacitors, often used for filtering and conditioning of electronic signals, are acritical aspect of many high performance electronic devices. In many applications, tantalum capacitors are the capacitor of choice for a varie ...

"This program will lead to advanced high energy density composite metallized propellants that will ignite faster, burn more completely, more rapidly, and with less agglomeration than presently used fuels and thus, greatly improve rocket motor performance.Powder will be produced through a novel combustion process that couples industry-standard chemistry with a proven industrial powder production sy ...

"This program will lead to advanced high energy density battery materials that will generate more power than presently used materials and thus, greatly improve existing battery technology. Powder will be produced through a novel combustion process thatcouples industry-standard chemistry with a proven industrial powder production system. This process yields nanoparticles that are coated with sodi ...

DESCRIPTION (Provided by applicant): Although cell-based screening has been used successfully throughout the drug-discovery field, it is problematic when screening for antiviral compounds. This is because it requires inoculation of infectious virus onto the cells and the production of additional infectious progeny virus. Handling such infectious material is not easi ...

DESCRIPTION (provided by applicant): The goal of this proposal is to develop the commercial potential of a cell-based assay to screen for compounds with antiviral activity against filoviruses such as Ebola and Marburg viruses. The basis of this bioassay, which has been prototyped with respiratory syncytial virus, is infection-independent expression of a reporter gene from an artificial viral genom ...

DESCRIPTION (Provided by applicant): Hepatitis C virus (HCV) is the most prevalent chronic blood-borne infection in the U.S and a global health problem. Approximately 4 million individuals in the U.S. and 170 million individuals worldwide are chronically infected. As much as 40 percent of chronic liver disease is HCV related and this results in up to 10,000 deaths each year. Despite improvements, ...

DESCRIPTION (Provided by applicant): Hepatitis C virus (HCV) is the most prevalent chronic blood-borne infection in the U.S and a global health problem. Approximately 4 million individuals in the U.S. and 170 million individuals worldwide are chronically infected. As much as 40 percent of chronic liver disease is HCV related and this results in up to 10,000 deaths each year. Despite improvements, ...

"Fretting is a wear phenomenon that occurs between two mating surfaces: it is adhesive in nature, and vibration is its essential causative factor. Usually fretting is accompanied by corrosion. In general, fretting occurs between two tight fitting surfacesthat are subjected to a cyclic, relative motion of extremely small amplitude. Fretted regions are highly sensitive to fatigue cracking. Under fre ...

"Fretting is a wear phenomenon that occurs between two mating surfaces: it is adhesive in nature, and vibration is its essential causative factor. Usually fretting is accompanied by corrosion. In general, fretting occurs between two tight fitting surfacesthat are subjected to a cyclic, relative motion of extremely small amplitude. Fretted regions are highly sensitive to fatigue cracking. Under fre ...