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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 38821 results
  1. Development of a transgenic mouse line engineered to permit selection and cloning

    SBC: ABEOME CORPORATION            Topic: NCRR

    DESCRIPTION (provided by applicant): The Applicant proposes an improvement to monoclonal antibody technology through the generation of transgenic mice engineered to facilitate flow cytometric isolation and cloning of specific antigen-reactive plasmacytes. Monoclonal antibodies (mAbs) are arguably the most important biological reagents used in biomedical research, diagnostics, and therapeutics, and ...

    SBIR Phase I 2010 Department of Health and Human Services
  2. Personal Ozone Monitor

    SBC: 2B TECHNOLOGIES, INC.            Topic: NIEHS

    DESCRIPTION (provided by applicant): In this proposal we respond to the call by the National Institute of Environmental Health Sciences (NIEHS) in the PHS 2009-2 Omnibus Solicitation, Exposure Biology Program, Section 1, Technologies for Generating Precise Measures of Environmental Exposures for new products/devices, tools, assays to improve our ability to precisely measure environmental exposure ...

    SBIR Phase II 2010 Department of Health and Human Services
  3. Intravascular Cardiac Assist System for Decompression and Recovery

    SBC: ABIOMED, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): The objective of this proposal is to develop a less invasive long-term copulsation device to treat patients in late Class III and early Class IV stages of heart failure (HF). Chronic congestive heart failure is the largest unsolved problem in cardiac care today. There are over 5.5 million people in the United States with this diagnosis and the number of patient ...

    SBIR Phase II 2010 Department of Health and Human Services
  4. A Novel Polymeric Percutaneous Heart Valve Prosthesis

    SBC: ABIOMED, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): The objective of this SBIR program is the modification of a polymeric trileaflet heart valve to a valve prosthesis that can be delivered percutaneously as a transcatheter aortic valve replacement. Key innovations include improved durability and hemodynamic properties, lower manufacturing costs, and simplified delivery over existing transcatheter bioprosthetic v ...

    SBIR Phase I 2010 Department of Health and Human Services
  5. Minimally Invasive Pediatric VAD for Treatment of Acute Heart Failure

    SBC: ABIOMED, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): The overall objective of this proposed program is the commercialization of the Pediatric Impella system, a minimally invasive ventricular assist device (VAD) for treatment of acute heart failure in pediatric patients. The device will be a less traumatic alternative to extracorporeal membrane oxygenation (ECMO), the current standard of care for these patients. T ...

    SBIR Phase I 2010 Department of Health and Human Services
  6. HealthCare Manager: A Remote Medication and Personal Health Plan Support System

    SBC: ABLELINK TECHNOLOGIES INC            Topic: NIA

    DESCRIPTION (provided by applicant): As the well known baby boomer generation surges toward retirement age, the issue becomes more significant each day of how this generation of 78 million seniors will be able to remain as independent as possible while increasingly burdened by the onset of multiple, chronic, medical conditions and a decline in cognitive abilities. Concurrent with the dramatic incr ...

    SBIR Phase I 2010 Department of Health and Human Services
  7. Software for improved scientific references using the Web-Citation Protocol

    SBC: ABRATECH CORPORATION            Topic: NLM

    DESCRIPTION (provided by applicant): This project will develop software for Web-based Compendia , which is defined as a concise, yet comprehensive, organization of a body of knowledge, together with its evaluation. Such Compendia will for a basis for Outlined-Knowledge on the Web. The software will use a new standard, the Web-Citation-Protocol. The Protocol offers a new method of creating refer ...

    SBIR Phase I 2010 Department of Health and Human Services
  8. Reducing Methadone's Arrhythmic potential

    SBC: ACADEMIC PHARMACEUTICALS INC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Methadone is an important long-term maintenance therapy for drug addiction and currently is frequently used for analgesia. However, methadone prolongs the QT interval on the electrocardiogram and this increases risk for life threatening arrhythmias and has led to the FDA's placing a black box warning on methadone's label. Initial studies in our laboratory hav ...

    SBIR Phase I 2010 Department of Health and Human Services
  9. Decreasing Calories, Fat and Sodium in Restaurant Meals for Widespread Industry Ado

    SBC: ACCENTS ON HEALTH, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): The prevalence of nutrition-related conditions (overweight/obesity, cancer, diabetes, heart disease, etc.) among Americans is widely documented. During the last twenty years, the frequency of dining out has increased, with Americans currently eating restaurant-prepared foods an average of five to six times per week. Compared to meals prepared at home, restauran ...

    SBIR Phase I 2010 Department of Health and Human Services
  10. Development of an anti-bias caster system

    SBC: ACCESSIBLE DESIGNS, INC.            Topic: NICHD

    DESCRIPTION (provided by applicant): The importance of reducing the incidence of secondary injuries related to manual wheelchair propulsion is undisputed. Based on several research studies, approximately 50% of manual wheelchair users (MWU) report symptoms of repetitive strain injury (RSI) related to the demand on the upper extremity during propulsion and transferring tasks. A substantial effort ...

    SBIR Phase I 2010 Department of Health and Human Services

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