Award Data

This proposal presents a Phase I SBIR project to develop a high precision, low disperse rate powder disseminator for the US Army. In the development of the sensitive detecting agent, we need to release a precise amount of C&B agents in the controlled detection experiments. However, such a technology does not exist at the present time. After examining existing technologies, we believe that the r ...

DESCRIPTION (provided by applicant): The aim of the proposed research is to develop tools for the prediction of the distribution of drug compounds in the human body. There is currently no experimental high throughput screening (HTS) method for determining compound tissue distribution. A drug compound's propensity to be taken up by different tissues and organs affects whether it will reach its acti ...

We propose to continue the development and characterization of a polymeric nanoencapsulation technology that can increase the lifetime of a protein therapeutic agent within a biological system. The materials have been demonstrated to exhibit no cytotoxicity and to efficiently deliver antibody against Protective Antigen of bacillus anthracis.

We propose that a comparative colorimetric assay be developed that will use a ticket of the same dimensions as the current ANP immunoassay tickets. This will allow the AChE test to be conducted using a similar workflow as the lateral flow immunoassay-based HHAs and be similarly read on the ANP reader to yield an unambiguous result independent of user judgment.

ANP Technologies proposes to develop a sample concentration system that uses commercial hollow fiber filtration technology with permanent anti-fouling coatings to concentrate biological contaminants in water sources or supplies to a level high enough to be readily detected. The filter technology will allow simple and quick release of the contaminants into a much smaller volume without the use of ...

DESCRIPTION (provided by applicant): LED based curing lights are beginning to replace conventional halogen lamps as the first choice for dental photo-curing applications. The target of this proposal is to develop a new generation LED dental curing light. It will be the first curing light that is optimized according to the kinetic response of the dental composite, which plays a key role in determin ...

Low-light-level photodetector arrays are proposed for detecting the weak optical emission spectra from the trace atoms in the laser-induced breakdown spectroscopy (LIBS). The proposed semiconductor image intensifier and low-light-level camera utilize the miniaturized and monolithically integrated version of a proven solid-state detector technology, and is expected to be able to detect femto-watts ...

Ethylene is a growth hormone for fruits and vegetables that is generated by the plants themselves; that is, it acts as a self-ripening agent. Hence, the removal of ethylene gas can play a central role in maintaining the freshness of these products. Whereas the temperature and the levels of oxygen and carbon dioxide gases are also important system variables that demand a significant economic invest ...

The conversion of corn and other biomass to fuel grade ethanol not only would reduce U.S. dependence on foreign energy sources but also would be a major industrial application for agricultural products. However, the process of drying the ethanol to fuel grade consumes significant amounts of energy, incurring costs that continue to increase as cost of natural gas increases. This project will deve ...

The need for natural gas continues to grow, and recent increases in petroleum prices have been paralleled by large increases in the price of natural gas. However, natural gas at the source often has high concentrations of carbon dioxide and hydrogen sulfide, which must be removed. Although existing commercial polymeric membranes (e.g. cellulose acetate and polysulfone) do a good job of sweetenin ...