Award Data

DESCRIPTION provided by applicant andquot ClotFoam R andquot is a novel adhesive sealant composition and second generation hemostatic agent This biological agent was designed to arrest moderate to severe blood loss arising from intracavitary traumatic injury or intraoperative hemorrhage without compression stitches or staples Control of Intraoperative hemorrhage in laparoscopic surgery whi ...

DESCRIPTION provided by applicant Current NIGMS SBIR funding supported InvivoSciences LLCandapos s IVS launch of several product lines in IVS generated revenues from the sales of three dimensional D cell culture tools MC TM and IVS InsertsTM that can grow various hydrogel tissues without any support layers The culture tools enable Palpator TM and Tissue StretcherTM to stretch the ...

DESCRIPTION provided by applicant Synthonics is developing the metal coordinated levodopa drug product MCP for FDA approval Levodopa has served as a primary pharmacotherapy for patients with Parkinsonandapos s disease PD for years and it remains uniquely effective However replacing dopamine by administering levodopa in a standard formulations results in pulsatile delivery charact ...

DESCRIPTION provided by applicant Cerebral ischemia is a major cause of death and long term disability with high accompanying social and medical costs Approximately Americans suffer a stroke each year at an estimated annual cost of $ B American Heart Association Heart Disease and Stroke Statistics Update Substantial preclinical data support the use of NMDA receptor antago ...

DESCRIPTION provided by applicant In this revised Phase II the project will develop and evaluate a set of five online training workshops designed to help foster adoptive and kinship parents safely and empathically understand and reduce externalized behavior problems of children ages in their care following and throughout their placement The training incorporates emerging theory about complex traum ...

DESCRIPTION provided by applicant Excessive alcohol use is associated with a range of serious and costly health social and economic consequences at the individual and societal level This program of research serves as a venue by which to produce and test an innovative science based and cost effective means to intervene in a private convenient and individualized way with employed adults wh ...

New approaches to handling streaming data are required. By the time one wishes to index stored scientific data, critical decisions about what to store have already been made. We propose evaluating, extending, and implementing a suite of algorithms that use new indexing and sampling techniques to improve analytical performance on large heterogenous streams of scientific data beyond current state ...

An architecture for linking geographically disparate N-DOF test beds to facilitate real-time distributed operations is proposed. An industry supported middleware solution, OpenDDS, is proposed as a basis for the required simulation software. A survey of existing laboratory conditions is performed. Adaptation to existing laboratory conditions is provided through the abstraction of simulation requ ...

A new type of x-ray microscope is proposed for three-dimensional imaging of integrated circuits, or IC"s. The new microscope can image at resolutions down to 25 nm, and at speeds of over 10 million pixels per second. This imaging rate is over 1000x faster than existing high-resolution x-ray systems, and can image a full 1 cm chip in a few hours; existing x-ray microscopes would take years to accom ...

Efficient and accurate indexing is fundamental to the Big Data enterprise, but traditional indexing techniques are often foiled by noise and missing information. Aptima proposes CERTAIN (Certainty Enrichment via Relational and Temporal Analytical Indexing of Networks), a solution that advances several areas of large dataset indexing and applies them to the domain of cyber analysis. We will develop ...