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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10103

    Current drug discovery and development programs are severely limited by the expensive animal trials and oversimplified in vitro models. Results obtained from the in vitro models are not predictive of in vivo toxicity owing to significant difference in testing from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device for quantitati ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  2. Microfluidic High-throughput Platform for Determining of Kinetic Constants of Enzyme Variants

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10107

    Molecular biology techniques allow generating combinatorial libraries of large number of enzyme variants. However, there is currently no technology available for screening the enzyme libraries for identifying variants with improved activity for the substrate. We propose to develop a novel, microfluidic, high-throughput platform for determining kinetic constants of enzyme variants and identifying v ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  3. Novel MicroPower Source for Insect Based Sensor and Communication Platforms

    SBC: CFD RESEARCH CORPORATION            Topic: CBD09105

    Our objective is to develop a novel micropower source to be integrated with a microsensor, and communication chip on an insect, delivering a state-of-the-art unmanned chemical detection device. The biological fuel cell (Bio-FC) power source will leverage ongoing research at CFDRC and provide a compact/lightweight power supply for mounting on numerous types of insects and producing necessary power ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  4. MEMS Lamellar Based Interferometer for the Detection of Toxic Chemicals

    SBC: EPIR TECHNOLOGIES INC            Topic: CBD10104

    In order to satisfy the DOD and commercial needs for the detection and identification of chemical warfare agents, toxic industrial chemicals or biological compounds, we propose a compact, low-cost sensor based on the integration of HgCdTe photodiode detection technology with micro-opto-electromechanical systems (MOEMS) technology, which matches HgCdTe’s sensitivity with an inexpensive microscale ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  5. Focal Plane Array Technology for Passive Hyperspectral Standoff Detection

    SBC: EPIR TECHNOLOGIES INC            Topic: CBD10105

    Chemical imaging sensors require focal plane arrays (FPAs) comprising long wavelength infrared (LWIR) detectors suitable for hyperspectral detection. These detectors require high sensitivity to account for the low photon counts in narrow wavelength bands. The required sensitivity elevates the associated costs, so a need exists for a lower cost LWIR FPA for use with chemical imaging sensors. The te ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  6. Electrochemical Screening of Multiple Enzymes Relevant to Organophosphate Poisioning

    SBC: LYNNTECH INC.            Topic: CBD10108

    Organophosphorus (OP) compounds have been extensively used as pesticides and chemical warfare agents . Potential OPs exposure exists both on the battlefield and in the civilian sector. OPs exposure inhibits enzyme activity, allowing excess acetylcholine to accumulate. Screening of multiple enzymes is highly desirable because it may provide a comprehensive description of the warrior’s capacity fo ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  7. No Power Detection and Identification of Nerve Agents

    SBC: LYNNTECH INC.            Topic: CBD10101

    Rapid identification of asymmetric warfare modes, including unconventional chemical agents based attacks, is vital to the protection of U.S. armed forces personnel. Existing detection methods use bulky and expensive laboratory equipment to analytically determine the identity and concentration of chemical threats, negating their battlefield use. Colorimetric indicators such as the currently deploye ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  8. CBRN Sensor and Sensor Netting Algorithms

    SBC: Torch Technologies, Inc.            Topic: CBD09110

    information) During Phase I the Torch Technologies developed, demonstrated, and assessed the feasibility of an innovative, real-time multi-layered CW sensor data fusion network capability supporting advanced standoff detection and early warning against CB threats. Torch merged two significant technologies that we developed for the Department of Defense: 1) the ACRES CW multi-sensor data fusion t ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  9. Integrated Automated Pre-concentrator Inlet for Mass Spectrometer

    SBC: 1st Detect Corp            Topic: CBD09106

    This proposal describes a project to develop a pre-concentrator inlet system for a mass spectrometer. The pre-concentrator utilizes a heated mesh design that is coated with a variety of sorbent materials to provide high pre-concentration with adversely affecting the analysis time. An innovative method of evacuating the pre-concentrator chamber provides an additional gain in pre-concentration of 2 ...

    SBIR Phase II 2010 Department of DefenseOffice for Chemical and Biological Defense
  10. Oligonucleotide Enzyme Surrogate (OnES)

    SBC: Accacia International LLC            Topic: CBD08108

    Historically organophosphorus compounds such as insecticides and nerve agents have been susceptible to decomposition by proteinaceous enzymes. Organophosphate hydrolases (OPH) represent a practical method to deactivate such compounds peripherally and on surfaces. However, when such organophosphates are ingested, the use of proteinaceous enzymes such as OPH can be problematic because of their tende ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
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