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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 123258 results
  1. Improving Oral Health with Serious Games

    SBC: FIRSTHAND TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of this SBIR Fast Track research is to test the technical and scientific feasibility and educational efficacy of a suite of 5 serious computer games for improving oral health literacy. In English a nd Spanish, the games are designed to improve the oral health quality of life of young Americans at risk for severe tooth decay. Low levels of ...

    SBIR Phase I 2008 Department of Health and Human Services
  2. Efficient patient-specific cell generation by image-guidance

    SBC: DRVISION TECHNOLOGIES LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): This fast-track proposal applies advanced kinetic image pattern recognition (KIPR) technologies to predict induced pluripotent stem cell (iPSC) reprogramming colonies' differentiation outcomes for significantly improvedyield and robustness of differentiation protocols. The objectives of the proposed tool are 1) Teaching: creation of scores for induced colo ...

    SBIR Phase I 2011 Department of Health and Human Services
  3. Development of an Anti-P-selectin Antibody for the Treatment of Sickle Cell Disea

    SBC: SELEXYS PHARMACEUTICALS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Selexys Pharmaceuticals is developing a humanized monoclonal antibody drug directed against P-selectin for the treatment of vasoocclusive crisis in patients with sickle cell disease. P-selectin mediates the first step in the recruitment of white blood cells to sites of inflammation. Vasoocclusion is precipitated by a P- selectin-mediated adhesion of sickled red ...

    SBIR Phase I 2009 Department of Health and Human Services
  4. Tolerability of SRX246 in Huntington's Disease Patients

    SBC: AZEVAN PHARMACEUTICALS INC            Topic: 950

    DESCRIPTION provided by applicant Huntingtonandapos s Disease HD is an inherited disease that results from expansion of a trinucleotide CAG cytosine adenine guanine repeat that encodes a polyglutamine tract in the huntingtin protein Psychiatric symptoms including irritability and aggression are common in HD patients These are among the most distressing aspects of the disease They hav ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. A Therapeutic DNA Epitope Vaccine for Alzheimer's Disease

    SBC: ICHOR MEDICAL SYSTEMS, INC.            Topic: N/A

    Alzheimer's disease (AD) is the most common form of dementia in the elderly. It is estimated that there are currently more than 18 million people worldwide with AD and this number is projected to nearly double by 2025 to 34 million. The enormous, increasing worldwide healthcare burden of AD and the lack of effective drugs indicate new prophylactic and/or therapeutic approaches for treating AD are ...

    SBIR Phase I 2009 Department of Health and Human Services
  6. Optimization of a Therapeutic HIVSIV Multi-Antigen DNA Vaccine

    SBC: PROFECTUS BIOSCIENCES, INC.            Topic: NIAID

    DESCRIPTION: The HIV pandemic is one of the greatest public health challenges in history. It is estimated that 33 million people are living with HIV and 2.7 million of those are newly infected In a number of developed countries, the risk of death associated with HIV-1 infection has sharply declined due to the use of highly active antiretroviral therapy (HAART). Unfortunately, the rate of new HIV i ...

    SBIR Phase I 2014 Department of Health and Human Services
  7. Development of an Anti-PSGL-1 Antibody to Treat Crohn's Disease

    SBC: SELEXYS PHARMACEUTICALS CORPORATION            Topic: NIDDK

    DESCRIPTION (provided by applicant): The primary objective of this proposal is to develop and commercialize a safe and more effective therapy for the treatment of Crohn's Disease, an inflammatory bowel disease. Crohn's Disease is a chronic inflammatory disorder of the gastrointestinal tract that affects some 500,000 patients in the US. Selexys Pharmaceuticals is developing a fully human anti-PSGL- ...

    SBIR Phase I 2010 Department of Health and Human Services
  8. Development of a selective biosensor for detecting organophosphate exposure

    SBC: NAGY CONSULTING            Topic: N/A

    DESCRIPTION (provided by applicant): This SBIR project is in response to the call for the development of rapid and portable diagnostic tools for chemical threat exposure, suitable for use by emergency care providers in order to guide medical countermeasures. The broad objective of this proposal is to develop an extremely sensitive and selective biosensor device capable of detecting and discriminat ...

    SBIR Phase I 2006 Department of Health and Human Services
  9. Molecular breast imaging to guide early-stage patient care

    SBC: GAMMA MEDICA-IDEAS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Molecular Breast Imaging to Guide Early-Stage Patient Care Molecular Breast Imaging (MBI) will one day provide decision guidance for patient management without the need to perform a biopsy - that is without the need to cut out tissue that often is found to be normal. MBI's future benefit to women's health will obviate stressful watching and waiting periods of m ...

    SBIR Phase I 2009 Department of Health and Human Services
  10. Field Deployable, Automatic, EEG Seizure Detector and Brain Dysfunction Monitor

    SBC: CLEVELAND MEDICAL DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this Fast-Track SBIR proposal is to develop a portable, low-cost, field-deployable, automatic EEG-based seizure detector and brain dysfunction monitor for general civilian population under mass casualty conditions. It is envisioned that this system will be used as an essential component of rapid and aggressive management of seizures, crucial ...

    SBIR Phase I 2006 Department of Health and Human Services

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