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The characterization of biologically relevant polymetric materials is a major focus of the bioinstrumentation industry. Of particular interest is the rapid, direct sequencing of DNA through a nanopore as well as the characterization of other biopolymers. Although progress has been made with nanopore sequencing, some fundamental instrumental and system issues have so far kept the method from realiz ...

Gamma radiation detection has traditionally required single crystal materials that are difficult to produce consistently on an industrial scale. Agiltron has developed a new class of scintillator materials based on composites containing nanoparticles. These so-called nanocomposites exhibit radiation detection characteristics superior to currently available single crystal scintillators. In Phase I ...

Proposed here is the continued development of an innovative rheometer configuration design at NIST. It describes the determination of suitable detection, drive, control, software and assembly designs for a commercially viable, fully integrated device. The initial efforts will concentrate on examining the sub-systems of the design. An important feature of the proposed strategy is early commercial i ...

Standoff detection of nuclear materials continues to be one of the most critical tasks that security specialists must confront in a wide variety of applications, both military and civilian. There have been several approaches for standoff nuclear material detection. Each of them utilizes a different fundamental property of nuclear materials to improve the sensitivity of detection. In this SBIR prog ...

During Phase I, Yotta Navigation developed a proof-of-concept version of the MOUTman, envisioned to be a rugged, secure, high-precision, handheld real-time navigation system suitable for military operations. This system took advantage of Yotta Navigation expertise in several areas: inertial and GPS-assisted navigation, user interface design, efficient integration of components from mainstream supp ...

We propose the definition, design, and prototype development of a software tool for use by the U.S. manufacturing community to enable the automated production of design-based measurement strategies of known reliability and high economic efficiency for coordinate measuring machines (CMMs). The measurement strategies so generated will meet the objective of reducing overall costs to near-minimal valu ...

Certain lanthanide halides have significantly higher light output than NaI:Tl, the comparison standard for scintillators, plus other important properties, including fast decay times and excellent proportionality. Unfortunately, lanthanide halides grown by traditional melt processes have high production costs and limited availability. Crystals are usually limited to about 5x5 cm2, right cylinder, ...

Our society has become increasingly dependent on the reliability and proper functioning of a vast number of interconnected information systems. To improve the security of these systems, it is necessary to measure the amount of security provided by different systems and configuration since one cannot improve what cannot be measured. In this proposal, Intelligent Automation Inc. (IAI) and its consul ...

In this program, we propose to develop the Auto-limiting transmission lines using HTS. The first focus is to modify the NIST designs for fabrication by an outside vendor. The second focus is to fabricate the limiter designs using co-evaporation for deposition of the HTS material and compare the achieved device parameters. The third focus is the integration of the limiter onto a cryocooler. We will ...

Detection of chemical and biological warfare agents in a real-world setting is an increasingly urgent problem. Many of the current state-of-the-art sensors are aqueous based and require large biomolecules, such as antibodies, to achieve binding of the target molecule and subsequent reporting of the binding event. These technical hurdles are a drawback when considering deployment of these technol ...