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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A Better and Stable Cold High-Level Disinfectant Formulation for Medical Equipments
SBC: RANN RESEARCH CORPORATION Topic: N/ADESCRIPTION (provided by applicant): We are developing a novel two-part cold high-level disinfecting/sterilization technology that will be ready to work by mixing in water, just minutes before use. Both components separately are inactive stable derivatives of active high level disinfectant agents, have good shelf life, and easy handling restriction compared to dialdehydes, ensuring the cost-effect ...
SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health -
A Bioactive Prosthetic Vascular Graft
SBC: BIOSURFACES INC Topic: N/ADESCRIPTION (provided by applicant): Over 60,000 prosthetic grafts, which are comprised of either polyethylene terephthalate (polyester) or expanded polytetrafluoroethylene (ePTFE), are implanted in the United States each year. Medium (6-8mm) and small (l t5mm) internal diameter (I.D.) prosthetic arterial grafts continue to have unacceptably high failure rates when used in the clinical setting. T ...
STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health -
A biodegradable ophthalmic drug delivery device
SBC: Notus Laboratories, Inc. Topic: N/ADESCRIPTION (provided by applicant): Our long-term research goal is to develop an ophthalmic, nanofiber-based, biodegradable device that will provide extended release of therapeutic agents to the posterior segment of the eye via transscleral and intravitr eal approaches. This platform device will address the major technical problem in the treatment of posterior eye diseases (diabetic retinopathy, ...
SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health -
A Bio-manufacturing process for fabrication of 3D scaffolds with cell culture der
SBC: 3D Biotek, LLC Topic: N/ADESCRIPTION (provided by applicant): The objective of this research is to develop novel 3D biodegradable porous polymer scaffolds with biomimetic extracellular matrix (ECM) coating for tissue engineering application. This SBIR Phase I proposal is to demonstrate the scaffold manufacturing feasibility by using a proprietary precision extruding deposition technique to fabricate porous 3D tissue scaff ...
SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health -
A Breath-based Medicaton Adherence Monitoring System for HIVAIDS Therapies
SBC: XHALE, INC. Topic: N/ADESCRIPTION (provided by applicant): Building on our Phase I achievements, we will design and deploy a handheld, breath-based medication adherence monitoring system (adherence system) to identify adherence for clinical trials. The system consists of a miniature, battery powered gas chromatograph (the device) capable of measuring volatile metabolites (e.g., butanone) on an individual's breath after ...
SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health -
A Broadly Accessible Virtual Reading Tutor
SBC: MENTOR INTERACTIVE, INC. Topic: N/ADESCRIPTION (provided by applicant): Millions of children in the U.S. are at risk for learning to read well despite major advances in our understanding of the causes and cures for poor reading. In this Fast- Track proposal we propose to address this significant need and opportunity with a computer-based reading program that combines the power of one-on-one tutoring with the benefits of self-assess ...
SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health -
Abscription?-Based CpG Methylation Assays for Early Cancer Detection
SBC: Ribomed Biotechnologies, Inc. Topic: N/ADESCRIPTION (provided by applicant): This application is focused on the development of a simple and sensitive technology for the detection of CpG methylation in CpG islands of human cancer cells. CpG islands are short genomic segments in the promoter regio ns of most human genes that are enriched in the dinucleotide CpG. CpG islands are unmethylated in normal tissues but become progressively more ...
SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health -
Absolute Brain Oximeter For Rapid Bedside Measurements In Conscious Infants
SBC: I.S.S (USA), Inc. Topic: N/ADESCRIPTION (provided by applicant): Abstract ISS Inc. proposes to develop a novel non invasive instrument for quantitative monitoring of infant brain development. The instrument will be based on Frequency Domain Near-Infrared Spectroscopy technique and will feature eight (8) laser sources modulated simultaneously using the OFDM technology. The laser sources will emit at different wavelength. The ...
SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health -
Absorbable, Self-setting Bone Cement
SBC: POLY-MED, INC. Topic: N/ADESCRIPTION (provided by applicant): Since early development of polymethyl methacrylate bone cement (PMMA-BC), there have been many efforts to develop alternative compositions to circumvent some of its clinical shortcomings, which include (1) monomer cytotoxicity; (3) inability to form strong joint at the tissue-cement interface; and (3) being a permanent, non-absorbable implant, which may induce ...
SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health -
Accelerated Repair of Vascular Injury in Diabetes by TGF-beta Modified Stem Cells
SBC: BETASTEM THERAPUETICS, INC. Topic: N/ADESCRIPTION (provided by applicant): Accelerated Repair of Vascular Injury in Diabetes by TGF-beta Modified Stem Cells Abstract: Stem cells of hematopoietic origin (HSC) have been described that have the potential to repair vascular injury (CD34+ stem cells). We have recently demonstrated that a blockade of endogenous transforming growth factor-beta type 1 (TGF-21) in murine and human hematopoieti ...
SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health