Award Data

A GROWING NEED EXISTS FOR NEW AND IMPROVED SECOND-GENERATIONELECTROCHEMICAL BIOSENSORS CAPABLE OF RELIABLY DETECTING, MONITORING, AND ANALYZING A VARIETY OF CHEMICAL AND BIOLOGICAL COMPOUNDS IN THE ENVIRONMENT, IN PROCESS STREAMS,AND IN BODY FLUIDS. SUCH SENSORS WOULD FIND EXTENSIVE APPLICATIONS IN THE PREVENTION, DIAGNOSIS, AND TREATMENT OF MANY DISEASES; HOWEVER, IN THE UNITED STATES, ELECTROCHE ...

ALLOTECH, INC., WILL DEMONSTRATE A CATHODE RAY TUBE (CRT) DISPLAY THAT PRESENTS THE THREE-DIMENSIONAL CONFIGURATIONS OF COMPLEX STRUCTURES OF BIOMEDICAL INTEREST. THIS PROJECT WILL LIMIT ITS SCOPE TO STICK FIGURES OF MOLECULES. THE DISPLAY TECHNOLOGY PRODUCES THE VISUAL PERCEPTION OF STRUCTURE AND OF SPACE WITHOUT THE USE OF SPECIAL GLASSES OR OTHER OPTICS, USING A CONVENTIONAL CRT. THIS WILL BE A ...

THIS PROJECT WILL DEVELOP, PRODUCE, AND MARKET AN ADAPTABLE TUB AND ROLL-IN SHOWER FOR USE IN CONSTRUCTION OF ACCESSIBLEHOUSING FOR ELDERLY AND DISABLED INDIVIDUALS. THE ADAPTABLE BATHING FIXTURE WILL CONSIST OF A ROLL-IN SHOWER PAN AND REMOVABLE STANDARD-SIZE TUB BOWL. THE FIXTURE CAN BE INSTALLED AS EITHER A ROLL-IN SHOWER OR TUB AND CAN BE EASILY REFITTED TO MEET THE NEEDS OF THE NEXT OCCUPANT ...

N/A

N/A

THROMBOLYTIC THERAPY HAS BECOME AN INCREASINGLY IMPORTANT TOOL IN THE TREATMENT OF ACUTE MYOCARDIAL INFARCTION. THE MOST RECENTLY APPROVED THERAPEUTIC AGENT FOR THIS PURPOSE IST-PA (TISSUE PLASMINOGEN ACTIVATOR) WHICH HAS THE ADVANTAGESOF BEING FIBRIN SPECIFIC AND IS RAPIDLY CLEARED IN VIVO BY THE LIVER. THE DETECTION AND QUANTITATION OF THIS COMPONENTOF THE FIBRINOLYTIC SYSTEM AS WELL AS ITS INHI ...

THIS PROJECT WILL DEVELOP IMMUNOASSAYS FOR THE DIAGNOSIS OF NEUROCYSTICERCOSIS, AN INFECTION CAUSED BY THE LARVAE OF TAENIA SOLIUM. BOTH A DEFINITIVE TEST FOR THE DETECTION OF ANTIGENS IN THE CEREBROSPINAL FLUID OF PATIENTS SUSPECTEDTO HAVE THE INFECTION AND SCREENING TESTS FOR THE DETECTION OF ANTIBODIES IN SERUM WILL BE DEVELOPED. THE DIAGNOSTIC TESTS WILL UTILIZE ENZYME IMMUNOASSAYS ON THE EZ-S ...

THE OBJECTIVE OF THIS RESEARCH IS TO SHOW THAT A CARRAGEENAN-IMMOBILIZED WHITE-ROT FUNGUS, PHANEROCHAETE CHRYSOSPORIUM, WILL OXIDIZE AROMATIC HYDROCARBONS IN A STABILIZED ORGANIC SOLVENT AQUEOUS EMULSION. OXIDATION OF THE TEST AROMATIC HYDROCARBONS IN THE EMULSION WILL DEMONSTRATE THAT THE IMMOBILIZED LIVING FUNGUS CAN OPERATE AS A BIOCATALYTIC REACTOR. THE FEASIBILITY OF ORGANIC SUBSTRATE OXIDATI ...

DEVELOPMENT OF THE MABCANCER DATA BANK BY HYBRIZYME CORPORATION WILL ALLOW INTERESTED INVESTIGATORS TO IMMEDIATELY ACCESS THE MOST CURRENT INFORMATION AVAILABLE ON MONOCLONAL ANTIBODIES FOR USE IN THE DIAGNOSIS AND THERAPY OF CANCER. THE DATA BANK WILL BE COMPUTERIZED, UTILIZING THE TREMENDOUS DATA PROCESSING CAPABILITY NOW FOUND IN VIRTUALLY EVERY OFFICE AND LABORATORY. A PROTOTYPE WILL BE DEVELO ...

DEVELOPMENT OF AN INDIVIDUALIZED MEMORY PROSTHETIC DEVICE (IMPD) WILL PROVIDE BOTH REHABILITATIVE TREATMENT AND LONG-TERM COGNITIVE SUPPORT FUNCTIONS FOR PATIENTS WHO HAVE EXPERIENCED A TRAUMATIC BRAIN INJURY (TBI). APPROXIMATELY 500,000 PERSONS SUFFER A TBI EACH YEAR, WITH TOTAL ANNUAL COSTS ESTIMATED TO REACH $4 BILLION. A LARGE PORTION OF TBI PATIENTS ARE LEFT WITH PERMANENT MEMORY OR OTHER NEU ...