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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Development of P2X3 Ion Channel MAbs for the Treatment of Pain

    SBC: INTEGRAL MOLECULAR, INC            Topic: 100

    DESCRIPTION provided by applicant Acute and chronic pain resulting from injury surgery or disease afflicts andgt million Americans each year having a severe impact on mood mental health and quality of life and costing the U S approximately $ billion in economic costs annually For many patients treatment options provide inadequate relief because of the shortcomings of available th ...

    SBIR Phase II 2014 Department of Health and Human Services
  2. An Early-Phase Clinical Trial Evaluating ABC294640 in Patients with Refractory/Re

    SBC: Apogee Biotechnology Corporation            Topic: 102

    DESCRIPTION provided by applicant Diffuse large B cell lymphoma DLBCL represents one of the most common variants of Non Hodgkinandapos s lymphoma NHL and oncogenic herpesviruses EBV and KSHV are the etiologic agents for the majority of these tumors in patients over or those infected with the human immunodeficiency virus HIV Despite modest improvements in outcomes for patients rece ...

    STTR Phase II 2014 Department of Health and Human Services
  3. Vault-CCL21 Nanocapsule for Lung Cancer

    SBC: PROTEIN SCIENCES CORPORATION            Topic: NCI

    DESCRIPTION provided by applicant Lung cancer is the leading cause of cancer death in the United States and is responsible for more deaths each year than breast prostate colon hepatic renal and skin cancers combined Viewed in economic terms in the United States the value of life lost from lung cancer deaths in the year was more than $ billion which is estimated to rise to more t ...

    SBIR Phase II 2014 Department of Health and Human Services
  4. Motivational Interviewing: An Experiential Online Training Tool

    SBC: C4 Innovations, LLC            Topic: 104

    DESCRIPTION provided by applicant Between and the Center for Social Innovation LLC C developed and evaluated a prototype of the Motivational Interviewing Simulator An Experiential Online Training Tool The interactive case based multiplayer web based game allows service providers to deepen their skills in Motivational Interviewing MI a widely recognized evidence based prac ...

    SBIR Phase II 2014 Department of Health and Human Services
  5. Transforming Dialysis into a Controlled Drug Delivery System for Stem Cell Derive

    SBC: Sentien Biotechnologies, Inc.            Topic: 400

    DESCRIPTION provided by applicant The goal of this Phase IIB SBIR application is to test the Sentien cellular bioreactor product the Sentinelandquot in a first in man study to assess safety and preliminary efficacy Fifteen post cardiac surgery patients that are diagnosed with acute kidney injury and indicated for dialysis will be enrolled and connected to the Sentinel containing one of thre ...

    SBIR Phase II 2014 Department of Health and Human Services
  6. KL4 Surfactant to Mitigate Radiation-Induced Lung Injury

    SBC: DISCOVERY LABORATORIES, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Exposure to ionizing radiation from a nuclear reactor accident or deliberate terrorist actions including the detonation of andquot dirty bombsandquot is a significant public health concern The lung is particularly susceptible to ionizing radiation injury from external sources or inhalation of radioactive particles from radioactive fall out Radiation pneumono ...

    SBIR Phase II 2014 Department of Health and Human Services
  7. Rapid Test for Recent HIV Infection

    SBC: IMMUNETICS, INC.            Topic: R

    DESCRIPTION provided by applicant Monitoring the HIV epidemic to understand rates and patterns of growth as well as targeting intervention efforts to populations exhibiting high rates f HIV transmission are wholly dependent on determining the frequency of new infections using an assay that discriminates recent from long term HIV infection However very few HIV assays have been developed spec ...

    SBIR Phase II 2014 Department of Health and Human Services
  8. A serologic assay to measure successful Lyme borreliosis antibiotic therapy

    SBC: L2 DIAGNOSTICS, LLC            Topic: R

    DESCRIPTION provided by applicant Lyme disease LD caused by the Ixodes tick borne spirochete Borrelia burgdorferi Bb is the most common vector borne disease in the United States Despite public health preventive measures the annual confirmed case incidence has risen to over the vast majority of which occur in the Northeast Disseminated infection causes disease in the skin heart ...

    SBIR Phase II 2014 Department of Health and Human Services
  9. Electrochemical Home Monitoring System for Lithium Blood Level

    SBC: Giner, Inc.            Topic: 102

    DESCRIPTION provided by applicant Electrochemical Home Monitoring System for Lithium Blood Level Over the past years pharmaceutical lithium has been one of the most widely used and prescribed drugs for the effective treatment of bipolar disorder and other manic disorders Despite the long history of use and efficacy controlling patient blood levels in the narrow therapeutic range ...

    SBIR Phase II 2014 Department of Health and Human Services
  10. Dashboards for Clinician Monitoring of Patients Through a Mobile Sensing Platform

    SBC: COGITO HEALTH, INC.            Topic: 104

    DESCRIPTION provided by applicant Mental health disorders exact very high personal social and economic costs in our country and around the world presenting a significant public health challenge Clinicians and researchers are currently faced with the difficult task of inferrig patient behavior and treatment adherence between clinic visits through self report and historical behavior Cogitoan ...

    SBIR Phase II 2014 Department of Health and Human Services

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