Award Data

ABSTRACT: As the geometry of test articles becomes more complex the demand for evolving instrumentation to make global, quantitative surface pressure and temperature measurements across a diverse spectrum of test environments continues to increase. Traditionally, pressure sensitive coatings called pressure sensitive paints (PSPs) have been oxygen sensors. The need for a polymeric pressure sensi ...

Glioblastoma multiforme (GBM) is a malignant primary brain tumor affecting about 12,000 new cases per year in the U.S. Average survival is only about 14-15 months. Radiation (RT) is most commonly administered as 30 fractions of 2 Gray each over 6-weeks with concomitant temozolomide (TMZ). GBM tumors are hypoxic. The primary mechanism of RT is creation of singlet oxygen; hypoxia within GBM adversel ...

PROJECT SUMMARY. The skeletal muscle wasting that occurs with cancer cachexia compromises quality of life and is both directly and indirectly responsible for cancer mortalities. Tumor-derived and tumor-responsive factors as well as many therapeutics themselves contribute to the cachectic state, although nutritional support has little if any positive effect on restoring striated muscle mass or func ...

Technology Assessment & Transfer, Inc. and subcontractors propose novel, high performance additive manufactured (AM) heat exchangers for military systems. The AM process will allow for conformal, lightweight designs that optimize use of available space. Integrated computational materials engineering will be used to optimize the AM materials and process parameters, correlate material microstructure ...

Most of the existing efforts fighting against cyber-attacks in critical cyber systems are focused on achieving resiliency and survivability. However, there are specific mission requirements for certain types of critical cyber systems that demand for the mission software to fail/crash, as soon as possible, when cyber-attack is successful and a program control is lost, rather than to operate in some ...

Condition-based maintenance (CBM) has the potential to significantly reduce operating costs through improved equipment management and more informed scheduling of maintenance activities. Sensing hardware can monitor equipment health, apply diagnostic algorithms to evaluate an asset’s current state, and make projections for how the system will perform if damage is detected and tracked. For maintai ...

A process is proposed for manufacturing low-cost, high-quality, GaN-on-Diamond wafers, so as to enable production of high-power RFICs at costs that substantially outperform their equivalent circuits manufactured on GaN-on-SiC. The process utilizes an epitaxial transfer approach in which gallium nitride is grown epitaxially on silicon carbide handle wafers, removed from the handles, and bonded to d ...

In recent militaryengagements, thoracicinjuries occurred in nearly10% of wounded US personnel and are a primary orcontributingfactor in up to 75% of all civilian trauma-related deaths. Hemothorax, an accumulation of blood in the pleural space, is a common, lifethreatening result ofchest trauma.Whilethemajority of traumatic hemothoraces aremanaged by tubethoracostomy alone, in many cases ameasurabl ...

Parabon’s Snapshot DNA Phenotyping System, which stems from an SBIR Phase II project, predicts ancestry, pigmentation, and face shape from forensic DNA samples, giving investigators information about suspects or unidentified remains they could not have obtained previously. In December 2014, Snapshot was made commercially available, and since that time has been used in over 100 criminal cases. It ...

Technology Service Corporation (TSC) will develop innovative waveforms and exploitation algorithms for concurrent synthetic aperture radar (SAR) and moving target indication (MTI) in contested RF environments to counter emerging threats from commercial un