Award Data

Prostate cancer is the most common cancer of men in the United States with approximately 189,000 new cases and 30,000 deaths in 2002. Recurrent disease can be controlled temporarily with androgen ablation. However, almost all prostate carcinomas eventuall

DESCRIPTION (provided by applicant): Prostate cancer is the most common cancer of men in the United States with approximately 189,000 new cases and 30,000 deaths in 2002. Recurrent disease can be controlled temporarily with androgen ablation. However, alm

In Phase I, Kutta Consulting defined and detailed its vision for a Dismounted Associate (DA) that gives America's soldiers over-the-hill battlefield intelligence. Kutta, however, did not act alone. AATD, Boeing Phantom Works, General Dynamics, Advanced Ceramics Research, Neural Robotics Incorporated, 21st Century Systems, and numerous user groups contributed significant concepts, subject matter ex ...

DESCRIPTION provided by applicant There are unmet medical needs in the limited biologic therapeutics for adults with rheumatoid arthritis RA associated with $ billion annual US health care and societal costs These are due to inadequate efficacy prohibitive costs poor adherence and safety issues infections andamp malignancies Oral small molecule based therapies are warranted due to ...

DESCRIPTION provided by applicant The focus of this project is a novel immunomodifying therapy that provides protection from early allograft rejection in the absence of the standard toxic systemic immunosuppressive drug regimens This novel therapy is a nano barrier membrane called NB LVF consisting of a matrix made of laminin vitrogen fibronectin and type IV collagen NB LVF is applied to ...

Cryogenic superconductor electronics provides unique performance capabilities in speed and accuracy of digitization and signal processing. These capabilities enable advanced software-defined communication systems which can exceed the Objective requirements of advanced systems such as the Joint Tactical Radio System (JTRS). A key component required to effectively field superconductor electronics s ...

DESCRIPTION (provided by applicant): Hepatic fibrosis, a disease affecting tens of millions of patients worldwide, is the liver scarring response to chronic injury from viral hepatitis B or C, excessive alcohol use, iron overload or extrahepatic obstr

Nonlinearity of RF Power Ampifiers (PAs) produces harmonic and intermodulation distortion of communication signals, significantly limiting overall system performance. This is a particular problem for multi-carrier signals in a very broadband channel, especially those spanning multiple octaves, such as HF (2-30 MHz). Conventional approaches to deal with this problem are intrinsically narrow-band ...

Superconducting electronics have been proven to provide unique performance enhancements in speed and accuracy of RF digitization and signal processing. These capabilities enable OBJECTIVE performance to be achieved with the Joint Tactical Radio System (JTRS), and other software-defined communication systems. Superconductor Micro-Electronics (SME) technology, with its unique combination of high pe ...

DESCRIPTION provided by applicant Huge investments in pharmaceutical research and development over the past two decades have not produced many new drugs to help treat serious neuropsychiatric diseases The increasing failure rate for new drugs at all phases of clinical trials is at least partially to blame for this productivity crisis Despite extensive precinical testing the drugs either fail ...