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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. SBIR Phase II: Innovative Electroencephalography to Advance the Research and Diagnosis of Brain Disorders

    SBC: CREmedical Corp            Topic: BC

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is multi-fold: First, the proposed tripolar concentric ring electrode and instrumentation for acquiring brain signals, tripolar electroencephalography (tEEG), is a platform technology that has a variety of medical and commercial applications. By providing significantly clearer brain signals, ...

    SBIR Phase II 2014 National Science Foundation
  2. Effective Measures of Training Display System Performance

    SBC: Visual Performance LLC            Topic: N142104

    With over 80 years of combined experience in simulation and engineering, the four-member Visual Performance technical team will assess the feasibility of developing an objective and efficient measurement toolkit. The proposed design will meet, if not exceed, the minimum requirements set forth in the RFP.

    SBIR Phase I 2014 Department of DefenseNavy
  3. AAAPT Technology for Improving Chemotherapy

    SBC: Sci-Engi-Medco Solutions, Inc            Topic: NCI

    DESCRIPTION provided by applicant Dysregulation of apoptosis pathways and loss of Human Beta Defensin hBD are the common tactics adapted by cancer cells to circumvent the effects of chemotherapy Consequently high dose of chemotherapy is required to obtain a clinically relevant therapeutic index which in turn compromises safety and develops resistance to therapy The problem is acute p ...

    SBIR Phase I 2014 Department of Health and Human Services
  4. Adjoint-Based Shape Optimization for Noise Reduction


    ITAC and its partners propose to develop and demonstrate a computational technology and methodology tool for the concurrent automated shaping of aft airframe and nozzle geometries to reduce tactical aircraft jet noise without any performance penalties. The proposed technologies will lead to an integrated tool which inherently maintains critical aerodynamic performance while reducing the noise gene ...

    SBIR Phase I 2014 Department of DefenseNavy
  5. Innovative Designs for Reliable Electro-Explosive Ordnance Devices


    Missiles, use electro-explosive devices (EEDs) to perform mulitple functions during operation. This effort seeks ways to improve on the EED"s reliability and lower the failure or inadvertent activation rate of these devices. During Phase I, SEA CORP investigated replacing EEDs with commercial off the shelf (COTS) automotive airbag inflators to perform the required pneumatic functions of variou ...

    SBIR Phase II 2014 Department of DefenseMissile Defense Agency
  6. Experimental Design Software for Translational Gastrointestinal Microbiome Studie


    DESCRIPTION provided by applicant Design of experiments and test of hypotheses need to be available to research teams to develop and validate taxonomic metagenomic biomarkers in gastrointestinal tract GIT diseases The translational research team needs to design an experiment to test a hypothesis e g microbiota in Crohnandapos s disease is different than in normal controls calculat ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Development of Safe, Reliable, and Durable Lithium-ion Battery for Naval Aircraft Applications

    SBC: Yardney Technical Products, Inc.            Topic: N14AT006

    Yardney will design and develop a lightweight, safe, reliable, and cost-effective aircraft battery with improved thermal design and the use of active cooling techniques. As a novel part of the battery design, Yardney will investigate and implement high performance electrodes using three dimensional (3D) micro-porous current collectors, safer thin metal case cell design, a micro-channel heat pipe t ...

    STTR Phase I 2014 Department of DefenseNavy
  8. Rapid STEMI Fibrinolysis for Underserved Populations

    SBC: Pulse Therapeutics, Inc.            Topic: NIMHD

    DESCRIPTION provided by applicant Coronary heart disease CHD accounts for every of deaths in the United States US with acute incidences estimated at M annually Of these up to are classified as ST elevation myocardial infarction STEMI in which a clot blocks a coronary artery leading to a change in the ECG ST wave Because the heart muscle rapidly dies time to re ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. MIST System for Simultaneous Parallel Intracellular Delivery & Transfection

    SBC: OPENCELL TECHNOLOGIES, INC.            Topic: 400

    DESCRIPTION provided by applicant Alternative nanomaterial and gene transfer solutions are needed to access the potential held in intracellular imaging biopharmaceuticals gene therapy and stem cell research Delivery of small and macromolecules including nucleic acids drug molecules imaging agents peptides antibodies and enzymes into cells is criti ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Anti-virulence FimH inhibitors for the treatment and prevention of UTIs


    DESCRIPTION provided by applicant Over million women suffer from urinary tract infections UTI annually in the U S and approximately of these patients suffer from multiple recurrences UTI is unique in its high prevalence of chronic recurrent infections which has caused a tremendous need for long term conventional prophylactic therapy This is leading to increased antimicrobial res ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health

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