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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. DGPS-Based Trilateration Positioning Receiver

    SBC: Swaszek Peter            Topic: 07FH1

    Positioning and navigation have become a mainstay of everyday life in the U.S.; applications of interest include navigation of vehicles of all kinds, infrastructure mapping, and safety of life systems. Many of these recent applications have become possible through the GPS. With the recognized vulnerabilities of GPS, it is evident that equivalent backup systems must be developed. One possible so ...

    SBIR Phase I 2008 Department of Transportation
  2. SEED OIL DERIVATIVES AS ADJUVANTS WITH HERBICIDES

    SBC: Agsco Inc.            Topic: N/A

    RESEARCH AND DEVELOPMENT OF FREE FATTY ACIDS AND METHYL ESTERIFIED FREE FATTY ACIDS OF SEED OIL AS ADJUVANTS FOR PESTICIDE SPRAYS WILL BE CONDUCTED. LABORATORY EXPERIMENTS WILL BE CONDUCTED TO DEVELOP EMULSIFIER SYSTEMS FOR FREE FATTY ACIDS AND METHYL ESTERIFIED FREE FATTY ACIDS OF SEED OIL WHICH ARE COMPATIBLE WITH COMMERCIALLY AVAILABLE HERBICIDES. SMALL PLOT FIELD EXPERIMENTS WILL BE CONDUCTED ...

    SBIR Phase II 1988 Department of Agriculture
  3. Heartland Infrastructure Development Bank

    SBC: CEO Praxis Inc            Topic: N/A

    Infrastructure investment has been crucial to economic development throughout American history. Today there is a need for a sizeable investment in infrastructure, particularly in rural America and especially with respect to transportation and telecommunications. New facilities to distribute food and energy resources to the rest of the country will be needed. There is also a need for investment in ...

    SBIR Phase I 2008 Department of Agriculture
  4. Tribal Leaders Institute: On-line Training for Indian Nations

    SBC: SPIRIT LAKE CONSULTING, INC.            Topic: N/A

    The Department of the Interior alone appropriates over $2 billion dollars each year for the Operation of Indian Programs. This figure does not include billions of dollars that come into each reservation through grant funds from other agencies, private philanthropy, the $14.1 billion brought in from tribal gaming or other tribal enterprises. Much of this money never reaches its intended recipients, ...

    SBIR Phase II 2008 Department of Agriculture
  5. Engineered Spores as Fluorogenic Biological Indicators for Sterility Testing

    SBC: BCR DIAGNOSTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): BCR Diagnostics, Inc. (BCR) has recently developed and patented a technology platform for engineering fluorogenic functionality into living Bacillus spores. Fluorogenic spores (F-spores) produced at BCR appear to be phy siologically identical to normal spores except for performing as self reporters of initial germination events. Considering the unique features ...

    SBIR Phase II 2008 Department of Health and Human Services
  6. T1D Tolerance Induction with Natural Treg Epitopes

    SBC: EPIVAX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Type 1 (juvenile) diabetes is an organ-specific autoimmune disease resulting from destruction of insulinproducing pancreatic beta-cells. In non-diabetics, islet cell antigen-specific T cells are either deleted in thymic development or are converted to T regulatory cells that actively suppress effector responses to islet cell antigens. In juvenile diabetics and ...

    SBIR Phase I 2008 Department of Health and Human Services
  7. High Content Drug Screening with Cardiac Tissue

    SBC: MYOMICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Myomics, Inc. has developed High Content Drug Screening (HCS) technology for in vitro testing of compounds which alter contractile forces generated by miniaturized tissue engineered organs (Myo-Force Assay SystemTM, MFA STM). Myomics' 3-D tissue/force sensor composite is capable of long term studies (1-4 weeks) and provides force as well as electrophysiological ...

    SBIR Phase I 2008 Department of Health and Human Services
  8. A multi-user virtual Biology environment for discovery-oriented science education

    SBC: WOWIWE INSTRUCTION COMPANY            Topic: N/A

    DESCRIPTION (provided by applicant): This SBIR Phase 1 project is intended for consideration under the NIH Development of Discovery-Oriented Software and Tools for Science Education category through the National Center for Research Resources (NCRR) We pro pose to undertake a 6-month project aimed at studying the feasibility of re-purposing the North Dakota State University (NDSU) Virtual Cell pro ...

    SBIR Phase I 2008 Department of Health and Human Services
  9. Calcaftor, a CFTR stabilizer for Cystic Fibrosis treatment

    SBC: Calista Therapeutics, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Calista Therapeutics has invented Calcaftor, a first-in-class peptide drug that can treat all Cystic Fibrosis (CF) patients. Calcaftor is validated in the gold standard pre-clinical model of CF using F508 -CFTR lung tissue harvested from CF transplant patients. Results from this model demonstrated a gt25 hour duration of action that enables once daily inhaled n ...

    SBIR Phase I 2014 Department of Health and Human Services
  10. Inter-alpha-inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, LLC            Topic: NINDS

    DESCRIPTION (provided by applicant): Neonatal hypoxia-ischemia (HI) remains a major cause of acute perinatal brain injury, leading ultimately to neurologic dysfunction manifesting as cerebral palsy, mental retardation, and epilepsy. Cerebral oxygen deprivation and/or reduced blood flow due to umbilical cord occlusion, prolonged labor, and/or intracranial hemorrhage produce an inflammatory respons ...

    SBIR Phase I 2014 Department of Health and Human Services

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