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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. High-Field MR Compatible Dense Array EEG using Polymer Thick Film Technology

    SBC: Electrical Geodesics, Inc.            Topic: 108

    DESCRIPTION provided by applicant The goal of this SBIR project is to design a low profile high resistive MR compatible dense array EEG dEEG sensor net for simultaneous dEEG fMRI recordings in fields as high as Tesla This novel sensor net the andquot InkNetandquot will provide safe noninvasive and affordable dEEG fMRI technology to both clinicians and researchers thereby enabling r ...

    SBIR Phase II 2014 Department of Health and Human Services
  2. Preclinical development of novel small molecule malaria drugs that overcome drug

    SBC: DESIGNMEDIX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The worldwide health problem created by malaria has been made more difficult by the spread of drug resistant parasites We have developed an orally available and inexpensive class of novel drugs that act against both chloroquine resistant and chloroquine sensitive malaria This project carries on preclinical development of a drug candidate that has been select ...

    STTR Phase II 2014 Department of Health and Human Services
  3. Binary Static Previrtualization: Phase II

    SBC: Galois, Inc.            Topic: N131061

    Modular software development helps enable application developers to quickly write sophisticated applications. However, in most instances only a small fraction of the functionality included in a particular software component is needed. Not only is there a performance cost, but the prevalence of security vulnerabilities suggests that even unused functionality in binaries and shared libraries can be ...

    SBIR Phase II 2014 Department of DefenseNavy
  4. Pediatric Head Models for Improved Imaging of Neurological Development

    SBC: Electrical Geodesics, Inc.            Topic: 101

    DESCRIPTION provided by applicant While it is well known that the brain undergoes rapid developmental changes from birth to early childhood remarkably little is understood about the relationship between changes in brain size and composition and cognitive development Yet several potentially debilitating neurocognitive disorders are a consequence of delays or abnormalities in brain development ...

    SBIR Phase II 2014 Department of Health and Human Services
  5. Therapeutic Thrombin Analogs

    SBC: Aronora, Inc            Topic: NHLBI

    DESCRIPTION (provided by applicant): Project Summary/Abstract Treatment of acute ischemic stroke (AIS) with the thrombolytic/antithrombotic agent tissue plasminogen activator (tPA, Activase(R)) is limited due to the potential for severe hemorrhagic side effects. The first symptoms of acute ischemia to tPA treatment ( time to needle ) can span hours, even in developed urban areas, since an establis ...

    SBIR Phase II 2014 Department of Health and Human Services
  6. A Short Instrumented Test of Mobility for Neurological Disorders

    SBC: APDM, INC.            Topic: NICHD

    DESCRIPTION provided by applicant APDM is a young company focused on developing and commercializing professional systems using wearable inertial sensors for monitoring of human movement and movement disorders In Phase I we developed the novel Instrumented Stand and Walk test ISAW using APDMandapos s proprietary Opal movement monitors and Mobility Lab system We validated the ISAW by demon ...

    STTR Phase II 2014 Department of Health and Human Services
  7. A human cytomegalovirus-based immunotherapy for HIV-1

    SBC: TOMEGAVAX, INC.            Topic: NIAID

    DESCRIPTION The ultimate goal of this project is to develop an immunotherapy for human immunodeficiency virus HIV based on a spread deficient cytomegalovirus CMV derived vaccine expressing andquot tailoredandquot antigens designed for maximal coverage of clade B epitopes In non human primate models rhesus CMV vectored vaccines demonstrated unprecedented protection against highly virulent ...

    SBIR Phase II 2014 Department of Health and Human Services
  8. Therapeutic Thrombin Analogs

    SBC: Aronora, Inc            Topic: NHLBI

    DESCRIPTION provided by applicant Project Summary Abstract Treatment of acute ischemic stroke AIS with the thrombolytic antithrombotic agent tissue plasminogen activator tPA Activase is limited due to the potential for severe hemorrhagic side effects The first symptoms of acute ischemia to tPA treatment andquot time to needleandquot can span hours even in developed urban areas since ...

    SBIR Phase II 2014 Department of Health and Human Services
  9. Spherical Piezocrystal Transducers

    SBC: Btech Acoustics, LLC            Topic: N122142

    We propose the continued design, development and testing of spherical piezocrystal transducers and supporting technology including our gyroid transducer. The Phase II effort covers the modeling and demonstration of the gyroid transducer and comparison of performance with several piezocrystal and piezoceramic materials and testing in realistic environment. The electroacoustic performance will be es ...

    SBIR Phase II 2014 Department of DefenseNavy
  10. Web-Based Training for EAP Alcohol Screening, Brief Intervention, and Referral

    SBC: Oregon Center For Applied Science, Inc            Topic: 150

    DESCRIPTION provided by applicant Excessive alcohol consumption is a public health concern that causes approximately deaths each year in the United States and costs the economy an estimated $ billion in annual medical social and productivity losses Because the large majority of adults with alcohol disorders is employed and Employee Assistance Programs EAPs are resources i ...

    SBIR Phase II 2014 Department of Health and Human Services

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