Award Data

Today’s aerospace industry struggles to rapidly design, experiment, and field novel aerospace and defense capabilities because of the “lock in” business practices of major prime contractors. The rise of computational tools has not shortened design and build timelines over the last 50 years because their use has been offset by a “hard tooling” mindset investing in overly durable and compl ...

AI.Reverie’s simulation platform leverages the power of synthetic data to significantly improve the performance of mission critical vision algorithms. By generating fully annotated synthetic data at scale, the platform offsets the costs and time to label real world images and videos.  The program objectives are focused on improving the accuracy of computer vision algorithms for object de ...

Project Summary Sanfilippo disease (mucopolysaccharidosis type III; MPS III) is a devastating neurodegenerative lysosomal storage disorder of childhood whose pathologic features are neurologic: slowing of development, severe behavioral problems, progressive cognitive decline, dementia, and decline in motor skills leading to immobility, unresponsiveness, and death. We have focused on MPS IIID cause ...

Abstract: Femoroacetabular impingement or FAI is a commonly diagnosed condition affecting a younger patient population than the general osteoarthritis (OA) population. Untreated, FAI invariably leads to OA and, ultimately, total hip arthroplasty (THA). The fact that most FAI diagnoses are made in patients under the age of 40, with many in their late teens and twenties, makes FAI all the more clini ...

Synchrotron light sources and X-ray free electron lasers are now generating shorter pulses with more intense light than ever before possible. The capabilities of these new sources grant unprecedented access into the workings of the natural world. X-ray detectors, as they currently stand, cannot accommodate the large dynamic range of collected x-rays in modern scattering experiments. This capabilit ...

DESCRIPTION (provided by applicant): The aim of the proposed project is to develop an advanced, web-based knowledge management system for the creation and distribution of multilingual, patient-oriented documents. The system provides a vast library of pre-translated documents and document templates for medical, educational, and administrative materials used in patient-care. System users will be abl ...

Project Summary/Abstract:Fecal incontinence (FI), the involuntary soiling of various amounts of liquid and solid stool, is often devastating from a social, psychological, and hygiene perspective. Men and women suffer from FI equally with a range of 2 - 6% in people aged 20 - 30 years. The prevalence increases to over 15% in people older than 70 years1. FI may result from an isolated or combined lo ...

Weldments that join plates of aluminum or steel combat vehicle hulls can be the lowest strength area of the structure and thus provide a decreased level of ballistic protection. To avoid welds, seamless hulls could be formed from thick plate if a suitable manufacturing process is developed. Corvid Technologies, teamed with Concurrent Technologies Corporation (CTC) performed a series of modeling, s ...

PROJECT SUMMARY Under the parent grant award 2R44CA224460, Advanced Chemotherapy Technologies (ACT) developed an Implantable Iontophoresis Chemotherapy Delivery Device (ACT-IOP-003) that facilitates the infusion of a wide variety of chemotherapy agents directly into the cancer they are intended to treat, thereby minimizing systemic toxic exposure. ACT continues to focus specifically on treating pa ...

As a consequence of limited domestic agency over the supply-chain for microelectronics, adversaries have many opportunities for adversaries to infect mission critical systems with malicious software and hardware tampers. Therefore, to protect our pilots and their mission, we must develop new security solutions capable of deterring, detecting, and defending against adversarial actions against our t ...