List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Microcapillary Quartz Sensors for Screening Injectability of High Concentration Protein Formulations

    SBC: Qatch Technologies, LLC            Topic: None

    The objective of this SBIR Phase I proposal is to determine the feasibility of viscosity characterization of high concentration protein formulations (HCF) by QATCH’s microcapillary quartz technology. HCFs are non-Newtonian fluids with shear-thinning behavior and they are administered to patients by subcutaneous or muscular injections. The injectability of HCFs depends on the viscosity at high-sh ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Nanomachine Device for Semiconductor Process Control Monitoring

    SBC: Xallent LLC            Topic: None

    Conventional characterization and test methods are increasingly ineffective when applied to structures less than 100 nanometers, causing challenges across R&D, process control and failure analysis. An increasing number of subtle defects become prominent drivers of failure as device size and operating margins decrease, e.g., processing anomalies in thin gate oxides, substrate problems related to do ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  3. Continuous Learning for Additive Manufacturing Processes Through Advanced Data Analytics

    SBC: Senvol LLC            Topic: NA

    Additive manufacturing (AM) is a promising manufacturing technique for end-use parts that can solve challenges for American manufacturers in many industries, e.g. aerospace, defense, automotive, energy, and healthcare. However, despite the potential that AM offers, the rate of AM adoption in industry is very slow. This is because AM suffers from low repeatability and quality consistency issues, wh ...

    SBIR Phase I 2018 Department of CommerceNational Institute of Standards and Technology
  4. SWIFT ActiveScreener research and development of an intelligent web based document screening system

    SBC: Sciome LLC            Topic: NIEHS

    Project Summary More than systematic reviews are performed each year in the fields of environmental health and evidence based medicine with each review requiring on average between six months to one year of effort to complete In order to remain accurate systematic reviews require regular updates after their initial publication with most reviews out of date within five years In the sc ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Isochoric Pressure Assisted Vitrification of Testicular Tissue and Whole Testes

    SBC: Sylvatica Biotech, Inc.            Topic: NICHD

    This program aims to develop a novel method for cryopreserving human testicular tissue and whole testes which can also be applied to ovarian tissue and gonadal preservation and ultimately any cells tissues and whole organs This multi pronged approach builds on recent advances in machine perfusion nature inspired cytoprotection strategies and non toxic cryoprotectant solutions combining them ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Clinical evaluation of the novel uni directional Pd CivaSheet for Lung Cancer

    SBC: CIVATECH ONCOLOGY, INC.            Topic: 102

    CivaTech Oncology s mission is to provide improved radiation therapy directly to localized tumors The Company has developed a novel polymer encapsulated membrane like radiation source that emits radiation on only one side of the device the CivaSheet This directional source is compatible with open and minimally invasive surgical techniques and has FDA clearance to be used as primary or combin ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Noom Coach for Bariatric Surgery

    SBC: Noom, Inc.            Topic: 300

    Overweight and obesity have reached epidemic proportions in the United States As few behavioral treatments are effective for weight loss bariatric surgery is an increasingly important option Although these procedures are more helpful than psychosocial treatments post operative weight losses vary widely and a notable subset of patients demonstrate suboptimal weight loss or substantial weight re ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. A novel product for tendinopathy treatment

    SBC: NEW YORK R&D CENTER FOR TRANSLATIONAL MEDICINE AND THERAPEUTICS, INC.            Topic: NIA

    Project Summary This study aims to prove the concept and feasibility that TendonCure extracellular vesicles that contain signaling molecules i e exosomes secreted by mesenchymal stem cells i e tendon stem progenitor cells TSPCs or adipose derived stem cells ADSCs from individual patients donors cultured on a novel scaffold exert therapeutic efficacy on tendinopathy when injected into ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Tuned stem cell extracellular vesicles as a novel chronic wound therapeutic

    SBC: ZEN-BIO, INC.            Topic: NIA

    Project Summary The elderly population is rapidly increasing worldwide and those over years old are expected to comprise of the total population by These demographic changes will focus healthcare needs on those conditions more prevalent in the elderly Chronic wounds such as venous leg ulcers pressure ulcers and diabetic ulcers are over represented in the elderly population and even ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Evaluation of a therapeutic strategy to combat osteoarthritis

    SBC: biOOrg3.14 LLC            Topic: NIA

    ABSTRACT Osteoarthritis OA affects over million US adults it is one of the most common chronic health conditions and a leading cause of pain and disability among adults OA is a degenerative disease of the articular joints characterized by focal areas of cartilage fibrillation articular cartilage hypertrophy bon changes and eventual destruction of the articular surface Current FDA approv ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government