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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. EFFICIENT AND EFFECTIVE MOBILE DATA CAPTURE IN AN ACRIN CLIN TRIAL ENVIRON

    SBC: ADVANCED DIGITAL SYSTEMS, INC.            Topic: N/A

    N/A

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Nanoliter Lab-on-a-chip for Protein Crystallization

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): The human genome contains at least 30,000 unique open reading frames that may yield >100,000 polypeptide products. These products assemble into more than a million biologically relevant structures or proteins of interest per organism. Crystallization and X-ray diffraction of these proteins is routinely performed to determine their 3D structure which needs to be ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Nanoliter Lab-on-a-Chip for Blood Diagnostics

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): Latrogenic blood loss or "bleeding into the laboratory" is an important reason for administration of small volume transfusions in very low birth weight premature 6infants. A direct correlation was found between the volume of blood drawn for diagnostics and subsequent volume transfused. In neonatal infants, there may not be enough collected blood sample to perfo ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Nanodroplet PCR Lab-Chip for Clinical Pathogen Detection

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): Rapid and accurate detection and identification of pathogens is crucial for the effective management and treatment of infectious disease. While molecular diagnostic techniques including PCR are a promising approach for rapid and sensitive detection of pathogens, they suffer from a number of technical drawbacks which have slowed their acceptance in the clinic. ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. Nanoliter Lab-on-a-Chip for Rapid Parallel Immunoassays

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): The development of clinically effective cancer vaccines requires reliable analytical methods to evaluate the immune response to vaccination. Immunoassays are among the most sensitive and specific analytical methods that have been used widely in cancer vaccine research, most commonly to monitor the release of cytokines from T-cells in response to vaccination. A ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Integrally 3D Woven/3D Braided Composite Joining Elements For Ship Construction

    SBC: 3TEX, Inc.            Topic: N04093

    During Phase I, 3TEX designed universal, one-piece, 3D woven fiber preforms which can be used as either a “Butt” (H) joint or as a “P” joint as needed. Composite joints were fabricated and tested, demonstrating the benefit of the integral nature of the 3D preforms. 3D stress/strain and crack propagation analysis of composite Π-joint was performed using 3D MOSAIC code. 3D displacement, st ...

    SBIR Phase II 2006 Department of DefenseNavy
  7. 3-D Fiber Reinforced, Thermally Conductive Rotor Sheaths

    SBC: 3TEX, Inc.            Topic: N06T013

    Military helicopters rotors contend with rain, ice, sand, and flying debris. To prevent damage to the expensive blade protective sheaths or coatings are applied to the leading edge of the rotor blades. A 3-D woven composite sheath with high thermal conductivity fibers running through the thickness can offer the best qualities of both metal sheaths and elastomer coatings. Infused with an elastom ...

    STTR Phase I 2006 Department of DefenseNavy
  8. Improved Miller Fasteners Based on 3-D Braided Preforms

    SBC: 3TEX, Inc.            Topic: N06033

    Miller Fasteners made from 2-D laminates represent the state of the art in joining CMC panels to metal frames. Despite its success, the extant Miller fastener design is limited by its construction from a laminate of 2-D fabric. The resultant fastener part has poor interlaminar shear strength, and its manufacture and application entails high machining costs and high material scrap rates. 3TEX, i ...

    SBIR Phase I 2006 Department of DefenseNavy
  9. Discovery of Peptide-based Bone Morphogenic Protein Mimetics

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In this proposal, we present a novel approach for the identification and immobilization of a BMP mimetic. We plan to use phage display technology to identify peptides that mimic BMP-like signaling of the BMP receptors. These peptides will be linked to a previously identified high-affinity, collagen-binding peptide. The resulting hybrid molecule will allow contr ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Discovery of a Platelet Derived Growth Factor Peptide-based Mimetic

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Summary/Abstract Diabetic foot ulcers are a significant health problem that imposes high costs on both patients and society (Boulton, Vileikyte et al. 2005). A large proportion of foot ulcers remain unresponsive to available conventional treatment and their associated complications and costs have prompted extensive research that has led to promising breakthroug ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
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