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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Accelerated discovery of methylation targeted therapeutic development

    SBC: Epicypher, Inc.            Topic: 102

    PROJECT SUMMARYNucleosomesNucsare the repeating units of chromatinmade up of DNA wrapped around a histone octamerChanges in chromatin structurefunction can dramatically impact downstream gene expression and cellular physiologydriving oncogenic reprogramming and cancer progressionThis epigenetic regulation of chromatin is controlled by two major modificationshistone post translational modifications ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. A Comprehensive Newborn Screening Solution for Duchenne and Congenital Muscular Dystrophies

    SBC: BAEBIES, INC.            Topic: NICHD

    Congenital genetic abnormalities are a leading cause of childhood mortality and morbidity. While routine newborn screening (NBS) has dramatically improved health outcomes, many congenital disorders such as Duchenne muscular dystrophy (DMD) and other congenital muscular dystrophies (CMD) are not currently detected by routine NBS. Presymptomatic identification through NBS is critical to facilitate e ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Administrative Supplement for the Evaluation of the novel, uni-directional, Pd-103 CivaSheet for Lung Cancer

    SBC: CIVATECH ONCOLOGY INC            Topic: NCI

    Parent Award: R44CA217587 Clinical Evaluation of the novel, Uni-directional Pd-103 CivaSheet for Lung Cancers CivaTech Oncology’s mission is to provide improved radiation therapy directly to localized tumors. The Company has developed a novel, polymer-encapsulated, membrane-like radiation source that emits radiation on only one side of the device – CivaSheet®. This directional source is compa ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Advanced Indoor Navigation Aid for Blind and Visually-Impaired Individuals in Unfamiliar Spaces

    SBC: VORTANT TECHNOLOGIES LLC            Topic: N

    Project Summary Abstract Confusionbeing lostand losing track of oneandapos s orientation within large or unfamiliar indoor spacesthese are some of the biggest challenges facing people with visual disabilitiesSince GPS typically doesnandapos t work indoorsand isnandapos t fine grained enough anywayindividuals who cannot readily access visual information are at a significant disadvantageand many bli ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. AIR-MODULATED MATTRESS FOR THE PREVENTION OF DECUBITI

    SBC: Triangle Research and Development Corporation            Topic: N/A

    THIS PROJECT WILL INVESTIGATE THE FEASIBILITY OF CONSTRUCTING A UNIQUE AIR-MATTRESS SYSTEM FOR THE PREVENTIONOF DECUBITIAND THE ENHANCEMENT OF CIRCULATION. THIS ACTIVE,MUTABLE MATTRESS WILL BE CONSTRUCTED OF SMALL AIR CELLS, EACH OF WHICH WILL BE MICROPROCESSOR CONTROLLED AND PROGRAMMABLE BY THE END USER (THE CARETAKER OR PATIENT) TO CONTAIN THE DESIRED AMOUNT OF AIR. THE INFLATION LEVEL OF THE MA ...

    SBIR Phase II 1992 Department of Health and Human Services
  6. ALow Blood Volume Platform for Global Newborn Screening of Common, Treatable Conditions

    SBC: BAEBIES, INC.            Topic: NICHD

    An estimated 80% of babies born worldwide (approximately 100 million each year) currently do not receive any newborn screening care. Newborn screening (NBS) is an immensely successful testing program that identifies those at increased risk for common, treatable congenital disorders; the pre-symptomatic identification of these disorders in newborns enables the rapid initiation of treatments and red ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. A Low-Cost Platform for Routine High-Accuracy Sizing of Nucleic Acid Samples with 100 bp- 100 Mbp Dynamic Range

    SBC: Genturi Inc.            Topic: 172

    The goal of this project is to develop a microand nanofluidic DNA sizing platform with a sensitivityspeedand dynamic range that is unmatched by current sizing technologiesWe find that fluorescence burst analysis of individual DNA molecules transported through sub micrometer scale channels provides accurate and precise sizing of fragments betweenbp ands of MbpIn this singlemolecule sizing platformu ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. An Integrative Approach to Control Group Creation for Prevention Research

    SBC: PREVENTION STRATEGIES, LLC            Topic: 550

    PROJECT ABSTRACTThe goal of this Phase II SBIR project is to develop a method for creating algorithmically generated control groupsvirtual controlsThese will be composed of synthetic cases that have two characteristicspretest similarity to whatever prevention treatment group may present itself andpatterns of change over time that closely mimic the normal course of alcohol and drug use developmentT ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. A novel class of anti-acne therapeutics

    SBC: Verge Therapeutics            Topic: NIAMS

    Acne Vulgaris is a common skin disorder that affectsof the populationtypically teenagers and young adultsOvermillion people in the US are affected by acne generating a $billion market for acne treatmentsof which is derived from prescription medicationsAlthough acne is not a life threatening conditionit still has a high psychosocial impact resulting in depressionanxietyangersuicidal thoughtsphysica ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. A Novel Hernia Mesh to Improve Anchor Point Fixation and Prevent Hernia Formation

    SBC: Deep Blue Medical Advances, Inc.            Topic: 300

    Two million laparotomies are performed annually in the U Swith ventral hernia being a frequent complication inof patients and costing as much as $billion annuallyThe ten year ventral hernia recurrence rate is reportedlywithout hernia mesh andwhen a mesh is added to the repair and these numbers underestimate recurrence rates in the rapidly growing morbidly obese population in the USIn Junein the La ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
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