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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Low Cost and Rapid DNA-Based Biometric Device

    SBC: NetBio, Inc.            Topic: HSB091001

    Sensitive site exploitation activities are focused on collecting forensic evidence left behind by persons involved in terrorist or other illegal activity, and the biological evidence recovered is often referred to as"touch DNA samples". Touch samples include fingerprints, skin cells found on clothing (e.g. a shirt collar), and oral epithelial cells found on the opening of a soda can or the rim of ...

    SBIR Phase II 2011 Department of DefenseSpecial Operations Command
  2. Tissue Factor Antagonists for ALI/ARDS

    SBC: Altor Bioscience LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): The pathogenesis of ALI/ARDS involves both procoagulant and inflammatory mechanisms. Extravascular fibrin deposition in the lung is a characteristic pathologic feature of ALI/ARDS and intra-alveolar thrombi develop inthe lungs of patients with ALI/ARDS. Tissue factor (TF), the trigger protein for activation of the extrinsic coagulation pathway, has a direct ro ...

    SBIR Phase II 2011 Department of Health and Human Services
  3. Microfabricated Implantable Flowmeter for CSF Shunts Phase II

    SBC: Infoscitex Corporation            Topic: NINDS

    DESCRIPTION (provided by applicant): An implantable wireless flow sensor system has been under development that would enable measurement of the flow of cerebrospinal fluid (CSF) through the ventriculoperitoneal (VP) shunt, currently used to treat hydrocephalus patients. CSF flow is a key indicator of shunt function, and there is currently no way to measure it in situ, resulting in the absence ...

    SBIR Phase II 2011 Department of Health and Human Services
  4. Type III Secretion Inhibitors for Anti-Infective Therapy

    SBC: MICROBIOTIX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Pseudomonas aeruginosa infection is the leading cause of hospital-acquired pneumonia in patients undergoing mechanical ventilation. Current antibiotic treatments exhibit failure rates as high as 18%, even when the organism is susceptible to the antibiotic being administered. The goal of this project is to address this critical medical need by identifying specif ...

    SBIR Phase II 2011 Department of Health and Human Services
  5. Novel Diagnostic Sequencing System for HIV Resistance Testing

    SBC: INTELLIGENT BIO-SYSTEMS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): As of 2008 the CDC estimated that there were approximately 1.1 million persons in the U.S. infected with HIV- 1 and about 56,000 new cases are diagnosed each year. During the mid-to-late 1990s, advances in treatment slowed the progression of HIV to AIDS and related deaths. Unfortunately, the treatment often leads to the emergence of drug resistant mutants of HI ...

    SBIR Phase II 2011 Department of Health and Human Services
  6. Rapid sensitive low-cost test for resistant microbes causing hospital infections

    SBC: FIRST LIGHT BIOSCIENCES, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): We propose to develop a novel automated platform to enable rapid, sensitive, user-friendly, and cost-effective screening for the antibiotic resistant bacteria that frequently cause serious healthcare associated infections. Every year, about 100,000 deaths result from 2 million serious healthcare associated infections at an estimated cost of 35B. About 20,000 f ...

    SBIR Phase II 2011 Department of Health and Human Services
  7. Multi-Function Laser Radar (LADAR) for Rotorcraft Brownout and Cable Warning/Obstacle Avoidance

    SBC: H. N. BURNS ENGINEERING CORP.            Topic: AF093C137

    ABSTRACT: This proposed SBIR Phase II effort is to design, fabricate and field-test a prototype Multifunction Laser Radar System which will be integrated on a US Army Aeroflightdynamics Directorate (AFDD) EH-60L Blackhawk helicopter and flight tested in complete zero-visibility brownout conditions at Yuma Proving Ground (YPG). The primary objective of the proposed Phase II effort is to provide c ...

    SBIR Phase II 2011 Department of DefenseAir Force
  8. Confirmatory Immunoblot Test for Chagas' Disease

    SBC: IMMUNETICS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Chagas' Disease is a vector-borne parasitic infection of humans with Trypanosoma cruzi, which has recently been identified as an emerging and significant threat to transfusion safety and the blood supply. It is a chronic and potentially fatal condition which affects over 10 million people living in tropical regions of the Americas, is endemic in 21 countri ...

    SBIR Phase II 2011 Department of Health and Human Services
  9. Alzheimer's Disease Therapeutic

    SBC: APHIOS CORPORATION            Topic: NIA

    DESCRIPTION (provided by applicant): Alzheimer's Disease (AD) is a significant neurological disorder that afflicts more than 4.5 million Americans and more than 10 million people worldwide. The lack of a cure for AD will result in a demand for better and safer AD drugs. All of the drugs on the market today have serious side effects. Recently, researchers at The Blanchette Rockefeller Neurosci ...

    SBIR Phase II 2011 Department of Health and Human Services
  10. High Throughput, Label-Fee Molecular Interaction Platform for Membrane Protein

    SBC: MOLECULAR SENSING, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Molecular interactions form the basis of healthy metabolism as well as the manifestation of disease, and comprise the very foundation of drug treatment. Tools available to study molecular interactions in their nascent environment and physiological concentrations without chemical modification, such as surface immobilization or labeling, are limited. Current labe ...

    SBIR Phase II 2011 Department of Health and Human Services

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