List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Novel method to create knockout rats using endonucleases and spermatogonial stem

    SBC: TRANSPOSAGEN BIOPHARMACEUTICALS, INC.            Topic: 200

    DESCRIPTION provided by applicant The laboratory rat is a preferred rodent model in pre clinical drug studies Their larger size facilitates procedures otherwise difficult in mice includng studies using instrumentation blood sampling and surgeries and allows for ten times the amount of tissue collection Although rats are often more suitable than mice for pharmacological toxicological phy ...

    SBIR Phase II 2014 Department of Health and Human Services
  2. Biological vector control reducing arboviruses, including Dengue and Chikungunya

    SBC: MOSQUITOMATE, INC.            Topic: NIAID

    DESCRIPTION provided by applicant In the absence of effective approved drugs or vaccines vector control remains the only means of intervention for many against mosquito borne diseases This problem grows more complex with the recent establishment of multiple exotic mosquito species and mosquito borne pathogens Furthermore changing climate conditions are predicted to alter the traditional ra ...

    SBIR Phase II 2014 Department of Health and Human Services
  3. Catheter for Large Volume Intraparenchymal Brain Therapies

    SBC: TWIN STAR TDS, LLC            Topic: 105

    DESCRIPTION provided by applicant Neurodegenerative and malignant diseases of the central nervous system affect millions of Americans These diseases are often devastating and difficult to treat and effective drug delivery remains a significant challenge Infusion of drugs nto the brain parenchyma using convection enhanced delivery CED allows direct treatment of lesions circumventing the bl ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Therapy and Prophylaxis for Genital Tract Infection

    SBC: THERAPYX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Genital tract infection with Neisseria gonorrhoeae gonorrhea does not induce a state of specific protective immunity and can be acquired repeatedly Despite public health measures the disease persists at an unacceptably high frequency there is no vaccine against it and resistance even to the latest generations of antibiotics continues to emerge Recent fin ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Circulating Blood-Based Diagnostic for Mild Cognitive Impaired Victims

    SBC: ADVANCED GENOMIC TECHNOLOGY, LLC            Topic: NIA

    DESCRIPTION provided by applicant This project aims to generate blood tests for mild cognitive impairment MCI and conversion risk from MCI to full blown Alzheimerandapos s disease AD We have reported that systemic footprints increases in key micro RNA miR levels are identifiable in AD blood samples here we suggest that this is also true for MCI the pre AD phase Our recent ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. SBIR Phase II: Advanced Hydrodesulfurization Catalysts

    SBC: Advanced Energy Materials, LLC            Topic: NM

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is in removing sulfur compounds from various fuels such as diesel, gasoline and mixture of refined fuels known as transmix. It is critically important to reduce sulfur levels below 10 ppm as the emissions from transportation vehicles can cause acid rain and associated undesired effects. Sulfu ...

    SBIR Phase II 2014 National Science Foundation
  7. High Power, Long Endurance MnO2/CFx Battery for Sonobuoys Based on Interpenetrating Conductive Network

    SBC: Nanowise LLC            Topic: N142110

    The need for the United States Navy to maintain a superior global Anti-Submarine Warfare capability is heavily dependent on sonobouys and Navy has identified a need to develop batteries to power sonobuoys which have higher power capabilities than currently used technology. Nanowise LLC proposes to develop a high power MnO2/CFx battery based on interpenetrating conductive network of nanostructures. ...

    SBIR Phase I 2014 Department of DefenseNavy
  8. STTR Phase I: A Novel Abdominal Stimulator to Assist with Ventilator Weaning in Patients

    SBC: Liberate Medical LLC            Topic: BM

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project, in which a new device and approach to weaning patients from mechanical ventilation is proposed, is a reduction in public health care expenditure and a reduction in morbidity for the half a million patients who have difficulty weaning from mechanical ventilation each year in the US. This proje ...

    STTR Phase I 2014 National Science Foundation
  9. SBIR Phase I: A novel biological method to suppress Bacillus thuringiensis (Bt) Toxin resistance

    SBC: PARATECHS CORP.            Topic: BT

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is the development of a technology to sustain the efficacy of transgenic plants expressing the Bacillus thuringiensis (Bt) toxin. Transgenic expression of Bt toxins is a major tool for the control of insect pests in agriculturally important crops. Bt transgenic technology has been deployed on ...

    SBIR Phase I 2014 National Science Foundation
  10. SBIR Phase I: Innovative Platform Technology for Rapid Three Dimensional Micro Fabrication

    SBC: Hummingbird Nano            Topic: MN

    This SBIR Phase I project will reduce health costs and increase accessibility to diagnostics by reducing the cost of manufacture, and increasing manufacturing volume of superior quality microfluidic devices. The proposal seeks to develop a platform technology that produces the same manufacturing benefits as rapid prototyping and rapid manufacturing, though the resolution and surface finish will be ...

    SBIR Phase I 2014 National Science Foundation

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government