Award Data

ATA proposes to develop, test and deliver an Optical Inertial Reference Unit (OIRU) called the MSTAR Inertial Reference Unit with DRGs (MIRU-D). The MIRU-D will incorporate four ATA ARS-14s and four Boeing MEMS DRGs on the inertially stable side of the MIRU-D. The efforts in Phase II will lay the groundwork for a unit that is both technically superior and ready for flight qualification and manuf ...

ALTHOUG RENAL TRANSPLANTATION HAS PROVED TO BE BOTH USEFUL AND COST-EFFECTIVE COMPARED TO DIALYSIS, COMPLICATIONS ARE FREQUENT. MUST OF THE SUCCESS OF RENAL TRANSPLANTATION IS DEPENDENT UPON PROMPT IDENTIFICATION OF THE CAUSE OF IMPAIRMENT OF FUNCTION SO THAT APPROPRIATE TREATMENT CAN BE APPLIED BEFORE THE CONDITION BECOMES IRREVERSIBLE. ALTHOUGH NUCLEAR MEDICINE SYSTEMS AND SEVERAL METHODS OF ANA ...

DESCRIPTION (provided by applicant): We propose to develop and demonstrate a novel microfluidic device and assay for selection and optimization of delivery vehicles, specifically non-viral vectors for drug delivery to tumors. Tumor drug delivery is a complex phenomenon affected by several elements in addition to drug or delivery vehicle's physico-chemical properties. A key factor is tumor mic ...

DESCRIPTION (provided by applicant): The overall objective of this study is to develop a novel in vitro microfluidic platform to test a drug or delivery vehicle's ability to permeate the Blood-Brain Barrier (BBB). In contrast to current in-vitro models, our proposed device, SIM-BBB, comprises of a microfluidic two-compartment chamber. The chamber is designed in such a way as to permit vis ...

TECHNICAL RESEARCH ASSOCIATES, INC. PROPOSES THE DEVELOPMENTOF A NOVEL PLATELET-HARVESTING SYSTEM BASED ON A PREVIOUSLY DEVELOPED ULTRASOUND SEPARATION TECHNOLOGY. THIS TECHNOLOGY, DEVELOPED UNDER AN NHLBI GRANT, ALLOWS THE SEQUENTIAL SEPARATION OF CELLS BASED ON THEIR SIZE, EVEN THOSE CELLS THAT HAVE IDENTICAL DENSITIES. FIRST, RESIDUAL ERYTHROCYTES AND LARGE LEUKOCYTES CAN BE SEPARATED FROM PLAT ...

The MDA Director issued a directive necessitating the protection of Critical Program Information (CPI) from unintentional transfer and the policy for the implementation of anti-tamper (AT) technology on MDA acquisition and associated technology programs. AT technology consists of engineering activities that prevent and/or delay exploitation of critical technologies in U.S. weapons systems. The pur ...

DESCRIPTION (provided by applicant): This proposed project is motivated by the fact that comprehensive, broad-scale screening for eye diseases such as age-related macular degeneration (AMD), glaucoma, and diabetic retinopathy (DR), including advanced stages, is economically prohibitive without the introduction of computer-assisted diagnosis of retinal images. According to the CDC approximately 80 ...

Radiance Technologies proposes to perform advanced development, fabrication and demonstration an innovative low-profile, multi-layered anti-tamper (AT) volume protection"detect and react"sensor suite prototype that meets MDA requirements for portability and reusability. It utilizes radiation and vibration sensors to detect radiological and vibrational reverse engineering attacks, combined with tw ...

Although there have been many advances in optics for low energy x-rays, (

A compact x-ray laser driver with a high repetition rate is the subject of this phase I project. Most existing x-ray laser drivers are huge (1000s of square feet of floor space), expensive ($10,000,000+), have a low repetition rate (1/hr), are complex and require several PhDs to keep them working. Thus applications of present x-ray lasers are limited. In contrast, the proposed laser will occupy on ...