Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Developing Silicon Nanowire Sensors to Measuring Host-Cell Proteins at a Biomanufacturing Line

    SBC: Advanced Silicon Group            Topic: None

    Our biosensor is made of silicon nanowire arrays functionalized with antibodies to measure the concentration of specific proteins. In this grant we will take a sensor that has been demonstrated for use in measuring a set of generic host cell proteins and we will apply the sensor to measure a set of proteins for a specific cell line. In doing so, we will demonstrate the utility of our sensor to be ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  2. Multimode Chiroptical Spectrometer for Nanoparticle Characterization

    SBC: Applied Nanofluorescence LLC            Topic: None

    This project will develop a new scientific instrument optimized for the advanced characterization of near-infrared fluorescent nanoparticles that can exist as left- or right-handed structures (enantiomers). Single-walled carbon nanotubes (SWCNTs) are the leading current example of such nanomaterials. Applied NanoFluorescence, LLC (ANF) proposes a novel multi-mode chiroptical spectrometer that can ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  3. Advanced Manufacturing and Material Measurements Software Tool Weave ™ for the Acceleration and Automation of SEM Image Analysis in the Semiconductor Industry

    SBC: Sandbox Semiconductor Incorporated            Topic: None

    In this Phase I SBIR proposal, SandBox Semiconductor™ proposes to develop an Advanced Manufacturing and Material Measurements software tool called Weave ™ for accelerating and automating SEM image analysis for the semiconductor industry. During the development of a new manufacturing process line for a semiconductor device, tens of thousands of scanning electron microscopy (SEM) images are take ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  4. Gap-Free Model-Based Engineering for Manufacturing and Analysis: Digital Thread without Translation

    SBC: Nvariate, Inc.            Topic: None

    Modern Model-Based Enterprise / Engineering (MBE) systems rely on freeform surfaces built as complex combinations of geometric primitives to define engineered objects. Unfortunately, the intersection of freeform surfaces in MBE applications results in highly approximated solutions, degrading models that cost billions annually by US industry to fix. Current technology limits the abilities of users ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  5. Development of the JoRT Platform for Realistic Joint Reduction Training

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: DHA173002

    Joint reduction is a key skill and is a core competency for orthopedic surgeons deploying as part of a trauma team.Current training options are limited to classroom instruction on uninjured persons due to lack of a suitable training simulator. The first true reduction performed by medical providers is on actual patients. This method of instruction prevents the trainee from developing the comfort a ...

    SBIR Phase II 2019 Department of DefenseDefense Health Program
  6. Rapid At-home Test for Monitoring Tacrolimus Levels in Plasma

    SBC: Lynntech Inc.            Topic: A18145

    Vascularized composite allotransplantation (VCA) is a surgical approach for the clinical management of non-salvagable injuries. Tissue rejection is a major issue for patients receiving VCA. Tacrolimus is the most common immunosuppressant employed to minimize tissue rejections in VCA. The safety and efficacy of tacrolimus, which has a narrow therapeutic window is particularly sensitive to proper ma ...

    SBIR Phase I 2019 Department of DefenseDefense Health Program
  7. Complex Crystalloid Resuscitative Fluid

    SBC: GanD Inc            Topic: DHA172009

    Problem: Currently available resuscitation fluids have been shown to induce detrimental effects on trauma outcomes.Objective: The objective of this proposal is to use the data from the successful Phase 1 studies to guide the continued development and testing of the novel resuscitation fluid (GND-001), which has been designed to address the deficiencies of current resuscitation fluids.Proposed work ...

    SBIR Phase II 2019 Department of DefenseDefense Health Program
  8. Compact Speaker Array for Clinical Testing of Ear-level Devices

    SBC: FTL Labs Corporation            Topic: DHA18007

    While clinical audiometry is most often conducted with headphones, there are many practical cases where it is desirable to measure the free-space hearing performance of both normal-hearing listeners and listeners wearing hearing aids, hearing protection devices, or implantable hearing prosthetics, both for evaluating fitness for duty and for evaluating outcomes of clinical interventions. Tradition ...

    SBIR Phase II 2019 Department of DefenseDefense Health Program
  9. Low Cost Point-of-Care Diagnostic Platform for Reliable Therapeutic Drug Monitoring

    SBC: Triton Systems, Inc.            Topic: A18145

    Triton Systems, Inc, will develop a novel point-of-care (POC) diagnostic device for use in therapeutic drug monitoring (TDM). The proposed system will consist of low cost, easy-to-use devices that can perform quantitative analysis of immunosuppressive drugs, such as tacrolimus, within 5 minutes using only a drop of blood.

    SBIR Phase I 2019 Department of DefenseDefense Health Program
  10. Joint Dislocation and Reduction Simulator for Training

    SBC: Simetri, Inc.            Topic: DHA173002

    SIMETRIs effort to design, develop, and commercialize the Joint Articulation and Reduction Simulator (JAARS) integrates existing commercial manikin technology, presents multiple dislocation scenarios, and makes use of a modular design that includes Commercial Off the Shelf (COTS) and 3D printed components, with embedded sensors to provide student performance feedback as well as consumable expendit ...

    SBIR Phase II 2019 Department of DefenseDefense Health Program
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