Award Data

N/A

THE BIOCHEMICAL AND SYNTHETIC CAPACITY OF HIGHER PLANTS, AS SHOWN BY THEIR NATURAL CONTENT OF SUBSTANCES, HAS BEEN USED FOR CENTURIES IN SUPPLYING MATERIALS IMPORTANT IN PHARMACOLOGY AND IN FLAVORS AND FRAGRANCES. MANY OF THESE SECONDARY PRODUCTS ARE IN SHORT SUPPLY AND AN ENORMOUS EFFORT HAS TO BE EXTENDED TO GET THEM. ATTEMPTS TO USE CELL CULTURES OF HIGHER PLANTS AS A MEANS OF PRODUCING SECONDA ...

The Navy wants the capability of firing over twenty missiles with Mark 72 boosters compared to about a dozen today, which will require a different ablative material than what is currently used. A solution to this problem is needed to get ahead of the curve for the future fleet operations. There is an opportunity to develop new ablative materials for the Mark 41 Vertical Launch System (VLS) with th ...

ABSTRACT Neurodegenerative disordersincluding amyotrophic lateral sclerosisALSFriedreichandapos s ataxiaFAmultiple sclerosisMSDuchenne muscular dystrophyDMDAlzheimer s diseaseADParkinson s diseasePDand Huntington s diseaseHDare characterized by heterogeneous disease progressionEfforts to identify responder subgroups may uncover subgroups that are more homogeneous in disease related features than t ...

Outbreaks have become a significant public threat in hospitalsimpacting both patient lives and creating a financial burdenWith the increasing rise in antibiotic resistancenew interventions are urgently needed to contain ongoing outbreaksRecent studies have confirmed that whole genome sequencingWGSis able to identity unique mutations within each outbreak strainwhich can then be utilized to establis ...

THE TOPIC OF THIS PROPOSAL IS THE DESIGN OF AN ENVIRONMENTALCONTROL SYSTEM FOR THE MORE THAN TWO MILLION INDIVIDUALS IN THE UNITED STATES WHOSE PHYSICAL AND/OR MENTAL IMPAIRMENTS ARE SO SEVERE THAT THEY ARE UNABLE TO FUNCTION IN THEIR ENVIRONMENT IN A NORMAL AND EFFECTIVE MANNER. A TWO-YEAR COLLABORATIVE RESEARCH EFFORT BETWEEN THE BIOENGINEERING PROGRAM AT THE NATIONAL HEADQUARTERS OF THE ASSOCIA ...

Bioproduction is typically reliant on host-organisms to express the enzymes needed for a synthetic pathway, which suffers from drawbacks like wasted metabolic resources, feedstock toxicity, and purification. Cell-free bioproduction is the logical alternative, but one major drawback is stability of the enzymes in the absence of a cell. For cell-free bioproduction to be feasible, enzymes will need t ...

Project Summary This project proposes further development of a computational discovery platform shown to quantifiably identify and prioritize both targets and compounds for therapeutic intervention, which will accelerate the development of newer, more effective drugs with fewer side-effects. This platform is based on a novel fusion of two state of the art computational approaches (phenolog mapping ...

MAX phases are an important class of layered machinable ternary carbides and nitrides that exhibit a unique combination of ceramic and metal properties. In 2011, a new family of two-dimensional (2D) transition metal carbides, nitrides, and carbonitrides – called MXenes – was discovered via selective etching of the ‘A’ element from MAX phases. Texas Biochemicals Inc., has ...

PROCESSING OF SAR DATA IN REAL TIME REQUIRES HIGH SPEED COMPUTATION DEVICES CURRENTLY BEYOND THE STATE-OF-THE-ART OF CONVENTIONAL METHODS. DESIRED PROCESSORS MUST ALSO BE SMALL, RUGGED AND LOW POWER TO BE DEPLOYED ON AIRCRAFT. OPTICAL TECHNIQUES CAN SATISFY THESE REQUIREMENTS WITH IMAGINATIVE ARCHITECTURES. THIS PROPOSAL PRESENTS AN INNOVATIVE APPROACH FOR REAL TIME SAR IMAGE RECONSTRUCTION THAT C ...