Award Data

We propose maturation and extension of an innovative batch algorithm for track scene history reconstruction, and track refinement conditioned on this history, given input source track data from one or more sensors. The envisioned method is designed to process both kinematic data (e.g., track reports) and feature/discrimination data (e.g., useful to distinguish objects seen by multiple sensors to s ...

As more and more advanced hypersonic weapons are developed, vehicle temperatures are expected to near 1250°K (977°C); as flight times increase, these temperatures are expected to saturate the entire vehicle. Typically, forward-looking RF and IR sensors are collocated in the same protective radome, which degrades the performance of both systems. FIRST RF proposes a significantly different app ...

The Navy’s mission of global force projection and logistic support requires surface ships and naval aviation assets to be deployed worldwide with little supporting infrastructure for communications. Airborne units provide extended line of sight for network connectivity between surface vessels as well as contributing unique sensor capabilities. The use of unmanned aerial systems (UAS) as airborne ...

Clonogenic assays measure the ability of single cells to proliferate and form a colonyThis process approximates closely the regrowth and recurrence of tumors after treatment with radiation or chemotherapyproviding an assay to screen for drugs that block this processYetclonogenic assays are labor intensive and too cumbersome for high throughout screeningHTSof compound librariesHere we propose to de ...

Type 1 Diabetes (T1D) affects an ever growing population. While this disease typically has been associated with juveniles, the disease in adult populations is rapidly increasing. The defining clinical component is insulin loss, which occurs because of sustained inflammation in the islets. At present there is no means to prevent or reverse insulin loss. A major inflammatory pathway in T1D that cont ...

A simulation optimization tool can exploit existing BMDS simulation models to streamline the scenario generation analysis process. Our Phase II project will focus on using a simulation optimization approach to solve the problem of generating a minimal collection of test scenarios, using the minimum number of shared scenario components that meets a required set of test objectives. Each individual s ...

In severe persistent hyperinsulinism (HI), repeated hypoglycemic episodes can ultimately lead to permanent seizure disorders, learning disabilities, cerebral palsy, blindness and even death. Clinical studies have demonstrated the effectiveness of both short-term and long-term treatment with glucagon for severe forms of HI and continuous subcutaneous administration of glucagon has been recommended ...

Quantifying atmospheric aerosol, clouds and precipitation processes are critical needs for understanding and interpreting Earth’s changing energy budget, is a DOE objective, and is of broader benefit to the public. Specifically, the formation of ice in the atmosphere depends on the nature and abundance of ice nucleating particles, and has major implications for precipitation and cloud interactio ...

We present the design of a small, portable, microwave cold atomic clock that meets the frequency stability requirement of < 8X10-13 at 1 s averaging time and < 3X10-15 for an averaging time of 1 day. The entire clock is about the size of a desktop computer 18.75 ” X 14.75 ” X 8.77 ” (47.6 cm X 37.5 cm X 22.3 cm) and weighs 30.5 kg. The clock can run on both 100-240 VAC as well as +24 VDC. St ...

Achieving hypersonic flight with air breathing vehicles using logistics fuels is a demanding task. A significant challenge in the development of single use and reusable systems alike is ignition of the scramjet engine at low Mach numbers. Unfortunately, current ignition systems do not provide reliable performance at low Mach number. Therefore, there is a strong need for a significant ignition capa ...