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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Single-Cell Proteomic instrument for Predictive Product Quality Check in Autologous CAR-T Immunotherapies

    SBC: ISOPLEXIS CORPORATION            Topic: 102

    While CAR-T therapies have advanced in the clinic, there are still two specific issues using these breakthrough therapies for blood cancers: Durable responses in patients are only at 30-50% and Cytokine Release Syndrome occurs in 60-90% of treated patients. These limitations, for a drug that costs as much as $500,000, may cost an additional $250,000+ for treating adverse events leading to caution ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. 1 Micron Fiber Optic Receiver for Mil-Aero Environment

    SBC: PHASE SENSITIVE INNOVATIONS INC            Topic: N171031

    In this SBIR effort we will collaborate with Dr. J.C. Campbell’s research group at the University of Virginia (UVA) in developing a high-power, high-speed, high-linearity photodiode (PD) receiver optimized for operation at 1 micron wavelength. In phase II, we will fabricate, characterize, package and commercialize the 1 micron photodiode that we have successfully designed and studied in our phas ...

    SBIR Phase II 2019 Department of DefenseNavy
  3. A Novel, Nanostructured, Metal-organic Frameworks-Based Product Loss Prevention Technology in the Oil and Natural Gas Sector

    SBC: FRAMERGY INC            Topic: 18NCERP2

    To reach the end user, oil and gas production at the wellhead must be transmitted through the country and distributed to a wide range of customers. This logisticalsystem requires natural gas gathering lines, processing facilities,product storage tanks and Jots of other equipment. What results is air pollution caused by industry losses during these operations and the use of continuous or intermitte ...

    SBIR Phase II 2019 Environmental Protection Agency
  4. Microwave Photonic Radiometers for Weather Forecasting and Situational Awareness

    SBC: PHASE SENSITIVE INNOVATIONS INC            Topic: AF182001

    Passive Microwave Remote Sensing is currently utilized by AFRL, NASA, NOAA, and others to conduct Earth Science missions, including weather forecasting, early warning systems, and climate studies. Soundings of the atmosphere are conducted near several oxygen and water absorption lines at frequencies of ~20-200 GHz to determine key parameters of the atmospheric state, including temperature and humi ...

    SBIR Phase II 2019 Department of DefenseAir Force
  5. Next Generation Infrared Scene Projector for Testing MWIR Systems

    SBC: Chip Design Systems Inc.            Topic: AF18AT017

    Based on the results of Phase I, we aim to develop a prototype of the high speed dynamic IRSP instrument. This prototype will incorporate the next generation 1Kx1K IRLED array that is compatible with the highly successful and user-tested NSLEDS IRSP. If Phase II of the proposed project is successful, the result will be an upgrade of NSLEDS IRSP system to higher performance and operability. The rea ...

    STTR Phase II 2019 Department of DefenseAir Force
  6. Assessment of Peripherally Circulating Plasma Proteins and Clinical Risks toDifferentiate Epileptic Seizure from Psychogenic Nonepileptic Seizure

    SBC: Evogen, Inc.            Topic: 106

    Abstract Accurately diagnosing epilepsy is very challenging and time consuming because clinicians rarely observe the actual seizure, and there are many different types of seizures and epilepsy syndromes with differing presentations. Furthermore, other neurological disorders can be mimics of seizures leading to erroneous diagnosis, inappropriate treatments with significant potential adverse events, ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Production of Environmentally-Acceptable BioLubricants for Hydropower Applications

    SBC: RIKARBON INC            Topic: 15a

    Accidentally released lubricant into water bodies from hydropower production turbines and other marine (cruises, ships) applications challenges safe water recycling and management, and has invited a number of lawsuits.According to the Environmental Protection Agency, up to 16 million gallons of lubricants per year ? equating to 1.5 times the size of the Exxon Valdez spill ? are washed off into wat ...

    SBIR Phase II 2019 Department of Energy
  8. Evolving and Certifiable Autopilot for Unmanned Aerial Systems

    SBC: DESIGN ANALYSIS & RESEARCH CORP            Topic: A2

    An intelligent flight control system is developed with learning capabilities and a high degree of assurance that can be certified by the FAA and tested on a modular reconfigurable UAS.nbsp; Existing lack of intelligence, adaptability and high performance of current automatic flight controllers is addressed by taking advantage of high-performance computing platforms, state-of-the-art machine learni ...

    SBIR Phase II 2019 National Aeronautics and Space Administration
  9. Multi-Omic Single-Cell System for Improved Combination Cancer Immunotherapy Monitoring and Implementation

    SBC: ISOPLEXIS CORPORATION            Topic: 102

    IsoPlexis proposes to deliver a novel multi-omic method for targeted profiling of both the TCR sequence and proteome from an array of 1000+ single cells. Specifically, we will deliver a single-cell, TCR sequencing and protein capture assay for identifying responsive antigen specific TCRs, and concurrently evaluate these T-cells for functional response to that antigen. The challenge remains to link ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Low-cost Imager for Heavily Degraded Visual Environments

    SBC: PHASE SENSITIVE INNOVATIONS INC            Topic: A18040

    This project aims to develop a low-cost millimeter-wave (mmW) imaging system for ground vehicles, to operate in combination with a long-wave infrared (LWIR)camera. Such a system will mitigate the challenges of driving in degraded visual environments (DVE) including night time, fog, dust, or smoke by providing real-time image of the vehicle surrounding independent from the presence of naturally occ ...

    SBIR Phase II 2019 Department of DefenseArmy
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