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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Oligonucleotide Enzyme Surrogate (OnES)

    SBC: Accacia International LLC            Topic: CBD08108

    Historically organophosphorus compounds such as insecticides and nerve agents have been susceptible to decomposition by proteinaceous enzymes. Organophosphate hydrolases (OPH) represent a practical method to deactivate such compounds peripherally and on surfaces. However, when such organophosphates are ingested, the use of proteinaceous enzymes such as OPH can be problematic because of their tende ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  2. Handheld IR Raman Spectroscopy for Rapid Chemical Identification

    SBC: Aerius Photonics, LLC.            Topic: CBD08102

    Aerius Photonics and partner Ahura Scientific, propose to develop a handheld system, based on Ahura’s successful FirstDefender Raman system, that employs an excitation laser emitting at 980 nm and a low noise InGaAs array based on Aerius’ high performance InGaAs technology. This system will substantially reduce the fluorescence present in CCD-based systems, and unmask otherwise obscured spect ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  3. Ribozymes for In Vivo Degradation of G-Nerve Agents

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08108

    Given the possibility to administer prophylactic doses of protein bioscavengers inactivating OP nerve agents before they reach their acetylcholinesterase target, much attention has been given to proteins such as human butyrylcholinesterase and paraoxonase I. As small nucleic acid catalysts can exhibit triphosphoesterase activities, the identification of new molecules active against nerve agents w ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  4. Collective Protection for Military Working Dogs

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08103

    Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  5. Multiple Indication Adjuvants

    SBC: BIOPROTECTION SYSTEMS CORP.            Topic: CBD08105

    The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  6. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD RESEARCH CORPORATION            Topic: CBD07114

    Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  7. Omni-Directional, Wind and Water Tolerant Inlet for the DFU

    SBC: ENERTECHNIX, INC.            Topic: CBD07116

    The current DFU inlet exhibits poor aerosol sampling efficiency at high wind speeds. This project will develop an improved inlet with very high sampling efficiency for 1 to 20 micron particles at wind speeds up to 30 mph independent of wind direction. The project is focused on the DFU, but our Aerodynamic Next Generation Inlet (ANGI) will be beneficial for any high volume aerosol sampling applicat ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  8. Camouflaged liposome construct for efficient drug delivery across the blood-brain barrier

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: CBD08107

    A major obstacle to non-invasive treatment of brain injury and disease is the blood-brain barrier (BBB), which prevents many intravenously injected therapeutics from being taken into the brain. In this program, Luna Innovations and Virginia Tech propose to develop a novel liposome-based delivery system capable of delivering any of a variety of neuroprotective agents of use against organophosphate ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  9. Generic Adsorptive Carbon Residual Life Indicator

    SBC: MORPHIX TECHNOLOGIES, INC.            Topic: CBD07103

    Generic residual life indicator technology developed under PI effort will be matured through reduction of COTS items used in the breadboard design to a miniaturized brassboard system capable of detecting agent saturation front migration through a sorbent. The capability of this brassboard system to detect representative agents from several classes will be demonstrated along with the ability to pr ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  10. Automated Objective Speech Intelligibility Assessment System

    SBC: LI CREATIVE TECHNOLOGIES INC            Topic: CBD07106

    Based on the success of our Phase I feasibility research, we propose to continue the project for the automated objective speech intelligibility assessment system. It consists of a pair of head and torso simulators placed at the same distance as typical face-to-face communication, a power amplifier, a laptop computer, a speech recognizer, and console software. The simulator has acoustic properties ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
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