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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Targeting B-cell lymphoma with Leukothera-phase II

    SBC: Actinobac Biomed, Inc.            Topic: NCI

    DESCRIPTION provided by applicant B cell lymphoma is cancer of B lymphocytes and accounts for more than deaths in the U S each year While many patients respond to currently available therapy there is a high rate of cancer relapse and inability for the patients o tolerate chemotherapy Thus there is a significant need to make available to these patients newer therapies that are more e ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. RFID Based Tracking System for Ultra-Low Temperature Sample Repositories

    SBC: BIOTILLION LLC            Topic: 100

    DESCRIPTION provided by applicant The specific aim of this Phase IIb Phase II competitive renewal SBIR proposal is to advance the prototype systems we developed under our Phase II grant into commercial production Our product will be used to automatically track samples in laboratory and biobank freezers Most of these samples are stored in vials Between and million such vials are ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Oxalate Reduction by Oral Administration of Oxalate Degrading Enzymes

    SBC: CAPTOZYME LLC            Topic: 400

    DESCRIPTION provided by applicant Severe oxalate related conditions such as primary hyperoxaluria PH secondary hyperoxaluria SH as a result of short bowel syndrome chronic inflammatory bowel disease cystic fibrosis post bariatric and other malabsorption syndromes Zellweger spectrum disorders ZSD and chronic and end stage renal failure continues to be a healthcare problem without ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Integrated Bioinformatics Analysis Suite for targeted NGS of clinical specimens

    SBC: ASURAGEN, INC.            Topic: 400

    DESCRIPTION provided by applicant With the advent of rapid bench top sequencers such as the PGM and MiSeq the potential to transform cancer diagnosis and patient care is great Although sequencing instrumentation has become relatively affordable the need for NGS data analysis and interpretation still remains a big hurdle to the adoption of NGS based assays for many research and clinical labor ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. 2'-Fluorophosphophloretin (2FP)in the Treatment of Chronic Renal Failure

    SBC: DuoPhos            Topic: 400

    DESCRIPTION provided by applicant CKD chronic kidney disease is a progressive disease which is reported to affect of the worldandapos s population End stage renal disease ESRD is the fifth and final stage of CKD ESRD will affect million people worldwide in and more than Americans at a cost of more than $ billion in the U S alone Elevated serum phosphorus Pi is th ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a WNT Inhibitor for Advanced Stage Lung Cancer

    SBC: Stemsynergy Therapeutic            Topic: 102

    DESCRIPTION provided by applicant Non small cell lung cancer NSCLC is the most common lung cancer Half of NSCLC shows WNT activation marking poor survival StemSynergy Therapeutics Inc SSTI has identified a family of WNT inhibitors based on a novel chemical scaffold with our lead molecule SST demonstrating efficacy against WNT driven colorectal cancer In Phase I SBIR studies many ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Kiddio: Food Fight- Training Vegetable Parenting Practices

    SBC: Archimage, Inc.            Topic: N

    DESCRIPTION provided by applicant Higher vegetable intake has been related to lower risks of diabetes cardiovascular disease several cancers and obesity adiposity later in life Yet children are eating vegetables well below recommended amounts Parents are important influencers on the dietary intake of young children but they commonly report difficulty getting their child to eat vegetables ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Development of a turnkey system for assessing forelimb function in rats and mice.

    SBC: VULINTUS, INC            Topic: 108

    DESCRIPTION provided by applicant Millions of Americans are affected by neurological disorders such as stroke and spinal cord injury These disorders often result in impaired motor function and lead to significant disability amongst those affected Despite major efforts to develop therapies to alleviate the burden of these disorders virtually all promising preclinical therapies fail to success ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. A novel broad-spectrum influenza vaccine

    SBC: KJ BIOSCIENCES LLC            Topic: NIAID

    DESCRIPTION provided by applicant Influenza viruses constantly undergo antigenic changes which pose great challenges for development of vaccines against influenza epidemics as well as pandemics There are at least known subtypes of influenza A viruses which fall into two broad phylogenetic groups Current trivalent inactivated vaccines TIV H H and B for seasonal influenza are not suit ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Engineering of Human Corneal Endothelial Grafts

    SBC: BIOTISSUE HOLDINGS INC.            Topic: W

    DESCRIPTION provided by applicant The corneal endothelium plays a pivotal role in maintaining corneal transparency Unlike in other species the human corneal endothelium is notorious for its limited proliferative capacity in vivo after diseases injury aging and surgery Persistent corneal endothelial dysfunction leads to sight threatening bullous keratopathy Presently the only solution to ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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