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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Assessment of Peripherally Circulating Plasma Proteins and Clinical Risks toDifferentiate Epileptic Seizure from Psychogenic Nonepileptic Seizure

    SBC: Evogen, Inc.            Topic: 106

    Abstract Accurately diagnosing epilepsy is very challenging and time consuming because clinicians rarely observe the actual seizure, and there are many different types of seizures and epilepsy syndromes with differing presentations. Furthermore, other neurological disorders can be mimics of seizures leading to erroneous diagnosis, inappropriate treatments with significant potential adverse events, ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A SAFE AND COMPACT NEONATE TO ADULT NEUROIMAGING MRI SYSTEM

    SBC: ADVANCED IMAGING RESEARCH, INC.            Topic: 101

    NIH SBIR PA-18-871 w/o Clinical Trials A Safe and Compact Neonate to Adult Neuroimaging MRI System The intriguing human brain is the most imaged end-organ non-invasively, without ionizing radiation using magnetic resonance imaging (MRI). High spatial resolution brain MRI is an established diagnostic tool to assess injury mechanisms affecting newborn growth and the adult human connectome. To predic ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Extending WAAVES+: An animal and environment-agnostic, automated USV scoring platform for high-throughput social, behavioral, and neuropharmacological studies

    SBC: CORNERSTONE RESEARCH GROUP INC            Topic: 101

    Project SummaryUltrasonic vocalizations (USVs) are known to reflect emotional processing, brain neurochemistry and brain function - key observations in animal model studies. Collecting and processing USV data is time-intensive, manual, and costly. Most importantly, it limits researchers’ ability to employ fully effective, and nuanced experimental designs, and is a barrier to entry for other rese ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Ultra-Fast Combinatorial Analysis for Biomarker Discovery

    SBC: ROCKETML INC            Topic: 400

    Project Summary Abstract SignificanceOne of healthcare s largest challenges is that many patients do not respond to treatmentBy recent estimatesaroundof drugs are effective for less thanof patientsThis causes enormous physicalsocialand economic sufferingThe annual cost of ineffective treatment is estimated at $billion per year in the US aloneMoreovervariable treatment response contributes to the r ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Targeting Latexin for radiation mitigation.

    SBC: P2D, INC            Topic: NIAID

    The purpose of this grant is to develop novel therapeutic approaches for radiological/nuclear medical countermeasures. Very few medical products have been shown to counter the acute and long-term injuries that can result from a nuclear or radiological accident or attack. Medical products and regimens that mitigate and/or treat radiation injury post-exposure (i.e., administration of first dose to s ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Antithrombotic Protein C Activator for Hemodialysis

    SBC: ARONORA INC            Topic: y

    Project Summary Although potent antithrombotic drugs are availableall inadvertently target vital hemostatic mechanismsresulting in dose limiting hemorrhagic toxicity that restricts their useDue to a lack of safe thromboprophylaxisthrombotic thromboembolic blood vessel occlusions and vascular device failures remain among the leading causes of death and severe chronic disability in the U SConsequent ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. A randomized, placebo-controlled, single-blinded clinical trial to assess safety and efficacy of CD24Fc in controlling cardiovascular disease risks of HIV-infected patients

    SBC: Oncoimmune Inc            Topic: NHLBI

    Project Summary Abstract Infection with Human Immunodeficiency VirusHIVaffects an estimatedmillion worldwideIn the United Statesan estimatedmillion people are infectedAs the access to antiretroviral treatmentARThas increasedthe population of people infected with HIV live longerPatients with viral suppression have increased life expectancyHowevercompare to age matched individual without HIV infecti ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Diagnostic Test for Detecting Recent Seizures in Epilepsy Patients

    SBC: Evogen, Inc.            Topic: 106

    Project SummaryAbstractEpilepsy affects approximatelyof the world populationtotaling andgtmillion patientsWhile anti epileptic drugAEDtreatment is successful in many patientsof patients continue to experience seizures causing physicians to adjust change medications or other treatment parametersCurrent diagnostic tools are incapable of differentiating between patients experiencing a recent seizure ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. DR?1-MOG as a Next-Generation Immunotherapy for Methamphetamine Use Disorder

    SBC: VIROGENOMICS BIODEVELOPMENT INC            Topic: R41

    Methamphetamine use disorder is associated with damage to regions of the brain that control cognitive and psychiatric functionOne third to one half of adults with methamphetamine use disorder experience cognitive impairments and other psychiatric symptoms that significantly impact treatment outcomesincreased relapse and lower treatment retention ratesMounting evidence demonstrates how immune facto ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Humanized LMNA Animal Model for Detecting Pathogenicity in Clinical Variants

    SBC: NEMAMETRIX, INC            Topic: 400

    SUMMARYThe goal of this RSBIR grant application is to understand the role of genetic variation in LMNAFor cliniciansthe functional significance ofof the variations in LMNA have the status of being either unknown or a Variants of Uncertain SignificanceVUSAs genomic sequencing continues its expanded utilization into the clinicdiagnostic rates will improves as variant function becomes better assigned ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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