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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 173966 results
  1. Innovative Method for Strain Sensor Calibration on JSF Fleet Aircraft

    SBC: ATA Engineering, Inc.            Topic: N08025

    ATA Engineering, Inc., (ATA) developed and demonstrated a prototype SSCS for performing ground-based calibration of structural health sensors installed within the wings and horizontal/vertical tails of the F/A-18 aircraft. An automated user interface and...

    SBIR Phase II 2016 Department of DefenseAir Force
  2. Fully-Integrated Pressure and Temperature Sensitive Polymeric Nano-Coatings for Use in Hypersonic Facilities

    SBC: LeaTech, LLC            Topic: AF141232

    ABSTRACT: As the geometry of test articles becomes more complex the demand for evolving instrumentation to make global, quantitative surface pressure and temperature measurements across a diverse spectrum of test environments continues to increase. Traditionally, pressure sensitive coatings called pressure sensitive paints (PSPs) have been oxygen sensors. The need for a polymeric pressure sensi ...

    SBIR Phase I 2014 Department of DefenseAir Force
  3. Hybrid Battery/Supercapacitor Energy Storage Device

    SBC: ADA Technologies, Inc.            Topic: A15AT010

    ADA Technologies, Inc. (ADA) and Dr. Massoud Pedram at the University of Southern California (USC) have successfully completed a Phase I STTR effort for the development of a lithium ion (Li-ion)/ supercapacitor hybrid electrical energy storage system (HEESS) to afford pulse power characteristics (projected ~10 kW/kg) in a high energy system (100-150 Wh/kg). The system is enabled via a constant cur ...

    STTR Phase II 2016 Department of DefenseArmy
  4. Feasibility study of a novel noninvasive RF sensor for blood pressure measurements.

    SBC: Blumio, Inc.            Topic: NCCDPHP

    PROJECT SUMMARYABSTRACTHigh blood pressureor hypertensionis an important public health challenge because of its high prevalence and its role in increasing risk for a variety of other diseasesAccording to the American Heart Associationapproximatelyout of everyadults in the United States has hypertensionand the situation is projected to worsen with the percentage rising to approximatelyof the adult ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. Development of JR-220 (4-Chlorobenzylidenamino-guanidine hydrochloride) as a medication for alcohol dependence

    SBC: NAPROGENIX, INC.            Topic: 150

    Abstract Alcohol dependence affects at leastof the US populationwith a financial cost in excess of $BnPrevention of relapse in patients attempting to reduce alcohol consumption is a major therapeutic targetbut current treatments are ineffectiveand there is an urgent need for new medicationsMajor factors in causing relapse include the protracted symptoms of withdrawal from alcoholwhich are relieved ...

    SBIR Phase I 2017 Department of Health and Human Services
  6. Detecting Crack Nucleation/Damage Mechanisms In Sea-Based Aviation Environments

    SBC: TECHNICAL DATA ANALYSIS, INC.            Topic: N121099

    TDA proposes to continue their work on both corrosion sensor development and predictive modeling of corrosion damage with the vision of integrating sensor and modelling for adaptive prognosis of corrosion damage initiation in a unified framework. TDA focuses its research to understand the crack initiation from different electrochemical conditions and corrosion-deformation interaction effects in or ...

    SBIR Phase II 2016 Department of DefenseNavy
  7. Adaptive Clinical Efficacy Evaluation of ONC201 in Recurrent High Grade Glioma

    SBC: Oncoceutics, Inc.            Topic: 102

    Project Summary We propose a two arm adaptive Phase II clinical trial to evaluate ONCa selective antagonist of the G protein coupled receptorGPCRdopamine receptor domainDRDin recurrent glioblastomaGBMand diffuse midline glioma associated with very poor prognoses and limited treatment optionsDRDis overexpressed in high grade gliomas and controls Akt ERK signaling pathwaysDownstream of target engage ...

    SBIR Phase II 2018 Department of Health and Human Services
  8. Automation and validation of human on a chip systems for drug discovery

    SBC: Hesperos, LLC            Topic: NCATS

    Project Summary AbstractOur overall strategy for Hesperos is to utilize microphysiological systems in combination with functional readouts to establish platforms capable of analysis of chemicals and drug candidates for toxicity and efficacy during pre clinical testingThis is a service based company that is developing low cost in vitro systems containing a novelpumplessmicrophysiological platform a ...

    SBIR Phase II 2018 Department of Health and Human Services
  9. Development of an Open Speech Signal Processing Platform

    SBC: Flat Earth Inc            Topic: NIDCD

    This proposal will create an open speech signal processing platformThe open computational framework will be used for developing algorithms that will help accelerate acoustic and hearing science researchIt will permit researchers to more rapidly and easily test new algorithms with greater controlperformanceand easeSeveral example systems will be created to show that the platform can be adapted to a ...

    SBIR Phase II 2017 Department of Health and Human Services
  10. Riluzole Prodrugs for Melanoma and ALS

    SBC: Fox Chase Chemical Diversity Center, Inc.            Topic: 102

    We have discovered a novel Type IIb prodrug of riluzoletrigriluzoleFCBVHwhich has the potential to substantially improve therapy for the treatment of the devastating condition of metastatic melanoma acting via a novel glutamatergic mechanism of actionWhile riluzole has shown promising efficacy in treating melanoma in patientstrigrilluzole is andgtX more potent than riluzole itself in a Cmouse xeno ...

    SBIR Phase II 2018 Department of Health and Human Services

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