Award Data

Food production, and in particular animal-derived meat products, are a major source of green-house gases, compounded by the remarkable inefficiency in biomass conversion (grain to dense muscle tissue in meat), along with growing challenges with food safety, quality and nutrition. To address this growing problem, we propose to exploit the emerging field of cellular agriculture (tissue engineering o ...

Food production, and in particular animal-derived meat products, are a major source of green-house gases, compounded by the remarkable inefficiency in biomass conversion (grain to dense muscle tissue in meat), along with growing challenges with food safety, quality and nutrition. To address this growing problem, we propose to exploit the emerging field of cellular agriculture (tissue engineering o ...

Intelligent Optical Systems, Inc., in collaboration with Bowling Green State University, proposes to develop a field-rugged, eye-readable indicating spray solution that can immediately detect synthetic opioids over a large area of contamination (i.e., military vehicles, individual protective equipment, clandestine labs, etc.). The proposed chemosensor in a spray solution format will detect multipl ...

This project focuses on the design, integration and optimization of a flexible natural gas combined cycle plant with carbon capture, capable of operating in a highly variable renewable energy environment. Renewable energy sources such as wind and solar power offer unique solutions in our quest to reduce global carbon dioxide (CO2) emissions. However, the increasing penetration of these high variab ...

This project focuses on the design, integration and optimization of a flexible natural gas combined cycle plant with carbon capture, capable of operating in a highly variable renewable energy environment. Renewable energy sources such as wind and solar power offer unique solutions in our quest to reduce global carbon dioxide (CO2) emissions. However, the increasing penetration of these high variab ...

Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...

Through this STTR contract, we propose to evaluate the efficacy of our vaccine, FlowVax Marburg, in nonhuman primates (NHPs). This will be achieved through four Tasks. In Task 1, we will manufacture the vaccine in a quantity sufficient for the animal studies. In Task 2, we will perform MHC genotyping on a representative population of NHPs and, based on results, select a set of MHC-matched NHPs for ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terrible morbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditional vaccines have contributed greatly to public health, they have some limitations especially in the context of operati ...

Opioids, especially synthetic opioids, are a constant threat to the safety of civilian first responders; there are now serious concerns about their use in modern chemical warfare. Fentanyl and its many analogues (carfentanil, remifentanil, lofentanil, mefentanil, sufentanil, etc.) are extremely hazardous—if ingested or inhaled, many synthetic opioids cause lethal intoxication with only a few gra ...