You are here
The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
Development of Innovative Medical Device Technology for Quantifying Forces during Soft Tissue Manipulation Assessment and InterventionSBC: Health Smart Technologies, Inc Topic: R
PROJECT SUMMARY The lack of a means to quantify soft tissue manipulation (STM) motion and dose as delivered in the clinic is a critical problem in the reproducibility and therapeutic potential of this non-invasive and non-pharmacological modality. STM is a form of manual therapy used to evaluate and treat musculoskeletal pain, inflammation, and dysfunction. Different soft tissue forces have differ ...STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
SBC: Grannus Therapeutics, Inc. Topic: NEI
Abstract Aggregation of mutated myocilin (MYOC), a protein found in the endoplasmic reticulum (ER) of trabecular meshwork (TM) cells, disrupts the outflow of aqueous humor from the eye, causing increase in intraocular pressure (IOP), progressive retinal ganglion cell (RGC) death, and degeneration of the optic nerve, leading to primary open-angle glaucoma (POAG), characterized by irreversible visio ...STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
SBC: INNATEVR LLC Topic: NIDA
PROJECT SUMMARY/ABSTRACT Opioid Use Disorder (OUD) is a chronic, recurring condition that if left untreated, poses a significant and ongoing public health threat. OUD is associated with significant impairments in physical and psychological health including increased mortality and high utilization of emergency medical care as well as increased risk of Hepatitis C and HIV infection and Neonatal Abst ...STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
SBC: OpalGenix, Inc. Topic: NIDA
PROJECT SUMMARY FOR PREDICATE STTR PHASE I GRANT Perioperative and prescribed opioids often result in costly and unpredictable adverse effects, including life threatening respiratory depression and long-term opioid use/misuse in vulnerable patients. The US FDA warns against the use of codeine and tramadol in children due to postoperative anoxic brain injuries and deaths, and in nursing mothers due ...STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
SBC: Mekanistic Therapeutics, LLC Topic: 102
Mekanistic Therapeutics seeks to design, discover, and develop anti-cancer agents that selectively inhibit multiple oncogenic pathways. Among Mekanistic’s portfolio are dual and highly selective inhibitors of EGFR and PI3 kinase, which were rationally designed to only target these two critical oncogenes. The PI3 kinase (PI3K)/AKT/mTOR pathway plays a central role in driving tumor cell survival a ...STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
SBC: H3D, INC. Topic: DTRA20B002
This project aims to create a general-purpose readout architecture that will allow the rapid deployment of next generation detection systems. The system will be based on the development of a programmable general-purpose integrated circuit (GPIC) that has the front-end electronics required to read out signals from a variety of radiation detectors, especially next generation scintillators and semico ...STTR Phase I 2021 Department of DefenseDefense Threat Reduction Agency
SBC: BIOPTICS TECHNOLOGY LLC Topic: 105
ABSTRACT Many clinical situations, including stroke, expose the brain to insufficient cerebral blood flow (CBF) that cannot maintain normal cerebral metabolic rate of oxygen consumption (CMRO2) requirements, thereby leading to cerebral ischemic/hypoxic stresses and neurological disorders. Effective interventions are dependent on the findings of CBF/CMRO2 improvement and eventually neural recovery. ...STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
SBC: LGENIA INC. Topic: NIAID
Abstract Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is the biggest killer among infectious diseases. TB is also responsible for a quarter of all deaths associated with Antimicrobial Resistance (AMR). It is projected that by 2050, 75 million people, or one person every 12 seconds, will die due to AMR associated with TB. Long treatment times and increasing resistance to TB drugs ...STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
RememberStuff: a dyadic-focused technology to support persons with Alzheimer's disease in the communitySBC: EPERTURE LLC Topic: NIA
Project Abstract An estimated 5.7 million Americans have Alzheimer’s disease or a related dementia (ADRD) and one in ten people age 65 or older show symptoms of Alzheimer’s disease. As ADRD progresses so does the level of dependency on others. As the disease progresses, higher levels of dependence in people with Alzheimer’s disease are associated with significantly increased burden and costs ...STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
SBC: ALTALITY, INC. Topic: NIDA
PROJECT SUMMARY/ABSTRACT Pediatric opioid use is a public health crisis. In children, prescription opioids are the primary source of non- medical abuse as well as opioid-associated hospitalizations and deaths. Early opioid use in childhood is a known “gateway” to adulthood dependence and substance abuse disorders. Despite years of research, opioids remain the most commonly prescribed pain medi ...STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health