Award Data

In the setting of altitude-induced hypoxia, operator cognitive capacity degrades and can compromise both individual and team performance. This degradation is linked to falling brain energy (ATP) levels and an increased reliance on anaerobic energy production from glucose. Ketone bodies are the evolutionary alternative substrate to glucose for brain metabolic requirements; previous studies have sho ...

Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...

On this effort Toyon Research Corp. and The Pennsylvania State University are developing deep learning-based algorithms for object recognition and new class discovery in look-down infrared (IR) imagery. Our approach involves the development of a hybrid classifier that exploits both transfer learning and semi-supervised paradigms in order to maintain good generalization accuracy, especially when li ...

We propose to investigate, in collaboration with MGH Voice Center and Altec, Inc., application of surface electromyography (sEMG) to assessing cognitive workload, strain, and overload. Specifically, sEMG sensors placed on the face and neck will detect emotional/motor responses to workload strain. The proposed effort will build on the substantial sEMG experience of our partner, MGH (including resea ...

Adaptive Optics allow ground-based astronomical observatories to overcome atmospheric distortion limited observation by using natural and artificial guide stars to measure the distortion. Sodium-layer guide stars provide near all-sky coverage for high resolution astronomy. Over the last 20 years, Optically Pumped Semiconductor Laser (OPSL), also referred to as Vertically Extended Cavity Surface Em ...

Approximately 70% of sentinel events in medical care are related to communication mishaps, and despite regular and frequent occurrence, an even higher percentage (80%) of severe medical errors are related to miscommunication during handoffs (i.e., the transferring of information, responsibility, and authority for patient care from one provider to another). The TiER1 team proposes to address challe ...

The Department of Defense uses large-scale high-resolution federated simulations to propagate rocket vehicle trajectories. Runge-Kutta methods have served as a de-facto standard while conducting such simulations. However, there are several challenges while using Runge-Kutta methods for this task. Firstly, there should be exact time-step matching between federates, otherwise the states have to be i ...

The Ground-Based Interceptor (GBI) missile is the weapon component of the Ground-Based Midcourse Defense (GMD) system that consists of a rocket booster and kinetic kill vehicle. Recently, MDA has sought technologies to improve the performance of the booster vehicle (BV). To date, studies have shown that reductions in weight have a direct impact on overall effectiveness. The current proposal aims t ...

This STTR project develops an innovative seed fabrication technology to address the fundamental size-quality limitation of gallium nitride (GaN) substratesthe indispensable key component for GaN-based vertical high-power devices. Currently, there is no viable GaN technology to realize large-area and low-defect substrates simultaneously. The technology producing 6" and larger GaN wafers results in ...

To meet the U.S. Navy, specifically PMA-201, need for nondestructive evaluation (NDE) of concrete, including evaluating its strength, material properties, and damage localization, Luminit, LLC, and Southern Illinois University (SIU) propose to develop a novel Concrete Materials Characterization (COMAC) system, combining several methods of concrete characterization into a single sensor/software com ...