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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Information Salience

    SBC: DISCERNING TECHNOLOGIES, LLC            Topic: OSD11TD1

    Empirical-based mathematical framework and computer algorithms, for representing human perception and cognition processes and limitations, which influence the recognition of salient information about rapidly changing events.

    STTR Phase II 2015 Department of DefenseOffice of the Secretary of Defense
  2. Vulnerable Plaque Amplified Optical Analyzer

    SBC: Energy Research Company            Topic: NHLBI

    DESCRIPTION provided by applicant Energy Research Company ERCo in a collaboration with The City College of New York CCNY and Columbia University Medical Center CUMC proposes developing the Vulnerable Plaque Amplified Optical Analyzer VPAOA a fiber optic catheter instrument based on patented amplified spectroscopy technology for detecting and analyzing vulnerable plaque VP in corona ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. A Protective Tetravalent Vaccine Candidate for Dengue Fever Virus

    SBC: ALTRAVAX, INC            Topic: NIAID

    DESCRIPTION provided by applicant There are approximately million cases of dengue fever each year with billion people at risk mostly in low income countries There are four serotypes of dengue fever virus DENV and in its uncomplicated form the disease is worthy of its indigenous name andquot break bone feverandquot An individual may suffer sequential infections with multiple DE ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Novel Membrane Protein Solubilization/Stabilization Screen

    SBC: SOLUBLE THERAPEUTICS, INC            Topic: 100

    DESCRIPTION provided by applicant The increasing output of new integral membrane protein IMP structures is partially due to the availability of an increasing number of chemical variables such as detergents detergent like molecules lipids and solubilizing stabilizing additives It is clear that specific combinations and concentrations of these different variables are often necessary to impr ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Developing efficient and safe cell-permeable reprogramming peptides for generation of iPS cells.

    SBC: Vivoscript, Inc.            Topic: 200

    DESCRIPTION provided by applicant The groundbreaking discovery of induced pluripotent stem cells iPSCs has opened a new page for developing personalized cell based therapies against various devastating human diseases without ethical concerns of using human embryonic stem cells However the future clinical applications of iPSCs remain in doubt due to potential risks of undesired genomic alter ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Rapid Diagnostics for Mucormycosis

    SBC: VITALEX BIOSCIENCES, LLC            Topic: NIAID

    DESCRIPTION provided by applicant Mucormycosis most commonly caused by Rhizopus oryzae is a life threatening infection that occurs in patients immunocompromised by diabetic ketoacidosis DKA neutropenia corticosteroid use and or increased serum iron Because of the rising prevalence of these risk factors the incidence of mucormycosis has risen Despite disfiguring surgery and aggressive ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Enhancing Care of the Aged and Dying in Prisons

    SBC: KLEIN BUENDEL, INC.            Topic: NIA

    DESCRIPTION provided by applicant The United States has the highest rate of incarceration in the world The demographics of the prison population are shifting In fact the number of sentenced state and federal prisoners age or older grew at times the rate of the overall prison population from The health status of aging inmates does not mirror the free world population In fac ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. A high-throughput kit for detection of RNA modifications

    SBC: MAVERIX BIOMICS, INC.            Topic: NIDA

    DESCRIPTION provided by applicant The broad objective of this project is to develop an integrated wet lab dry lab kit for high throughput detection of RNA modifications The final product will provide all required molecular biology reagents a set of simple and robust experimental manipulations for facile analysis of modifications and researcher friendly analytic cloud based software requi ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Novel mass spectrometry methods for profiling modified RNA nucleotides in the nervous system

    SBC: Ribonova Inc.            Topic: NIDA

    DESCRIPTION provided by applicant Pseudouridine is the most abundant post transcriptionally modified nucleoside found in ribonucleic acid RNA Pseudouridine is an enzymatically generated isomer of the canonical base uridine with additional hydrogen bonding capabilities and appears to lead to local structural and biochemical effects within RNAs Pseudouridine has been detected in several type ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Development of Therapeutics to Treat Candida albicans Biofilm Infections

    SBC: BIOSYNESIS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The yeast Candida albicans is a normal resident of the human digestive tract It is also the most common fungal pathogen of humans causing both mucosal and systemic infections particularly in immune compromised individuals The majority of new C albicans infections arise from the presence of persistent C albicans cells existing in a biofilm These biofilm b ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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