Award Data

As a foundational component of a Layered Sensing architecture, Toyon proposes to develop a Multi-Modal Fusion Module (M2FM) capable ofconfirming detections from Chemical, Biological, and Radiological (CBR) sensing networks by fusing together information from other (non-CBR)sensors. In addition to confirming an initial CBR detection, M2FM will aid in characterizing the threat scenario by estimating ...

To address the CBDs need for a signal processing system designed to analyze and fuse data collected from chemical and biological sensors, Physical Optics Corporation (POC) proposes to further develop the Wavelet-Based Approach for Signal Processing and Analysis (WASP). WASP is based on novel application of Wavelet-based analysis to multimodal, multidimensional data available from a wide variety of ...

Typical procedures for respirator masks sizing and protective fit test are time-consuming and user intensive, requiring taking anthropometricmeasurements of the wearer, sampling the wearers breathing zone and the use of specialized tools and equipment. The proposed softwareapp aims to quickly, accurately and automatically perform respirator mask sizing and predict protective fit using only 2D imag ...

To address the CBDs need for adjustable optical correction technology for respiratory protective systems, Physical Optics Corporation (POC)proposes to continue the development of a new low-cost Adaptive Lens for Ocular Correction (ALOC). The ALOC is formed by thin-filmmicroarrays of wavefront correctors (MWCs), which are conformably laminated onto the facemask visor and controlled by a miniature d ...

A reliable, low-cost, low-power, adjustable, optical-correction technology for the Avon M50 respirator is proposed that is capable of deliveringthe eye relief needed by users needing visual correction with +/ 9 diopter correction in less than 100 ms, while maintaining a wide gaze angle.To achieve the application requirements, a series of freeform GRIN Alvarez lenses will be designed, fabricated, a ...

This project is a unique metagenomic evaluation of under-studied extremophilic microbiome natural products (NPs), with the goal of discovering novel antibiotic biowarfare agent (BWA) countermeasures. A metagenomic biosynthetic gene cluster library from extremophilic sources was created, sequenced, analyzed, and exploited to produce several broad-spectrum antibiotic extracts during the Phase I effo ...

Aflatoxins B1 (AFB1) are fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk for thedevelopment of hepatocellular carcinoma. Currently, there are no known countermeasures to selectively mitigate AFB1 toxicity. To meet thischallenge, we successfully validated a Phase I proof-of-concept study to harness the microbiome extracts of scavenging ma ...

We propose a high performance, cost-effective, universal Digital Assay Solutions platform with Mobile Readers, Assay Development and Calibration Software, and HIPAA-compliant cloud services for global health and defense applications. In Phase II project, we have developed the first generation product family receiving considerable interest from the assay manufacturers, government organizations and ...

The discovery and commercial development of licensed vaccines often take many years of research followed by years of pre-clinical and clinical development. We propose to assess the feasibility of using a novel irradiation-inactivation technology to develop vaccines more rapidly. The technology utilizes a manganese-peptide complex to protect antigenic proteins from ionizing radiation while allowing ...

EP Analytics Inc. will develop and commercialize a suite of easy-to-use performance profiling and prediction tools for characterizing the performance and energy efficiency of High Fidelity computer codes. DTRA uses High Fidelity codes to investigate weapon effects phenomenology and techniques for countering Weapons of Mass Destruction (WMD). End-to-end High Fidelity simulations in support of the D ...