Award Data

Many protein-based drugs have limited efficacy due to a short half-life or require intravenous delivery because of low bioavailability. Extend Biosciences is developing proprietary carrier molecules that allow proteins to access an intrinsic transport pathway for efficient delivery to the vascular space and then maintain a sustained presence in circulation. This novel technology would be of partic ...

The need for novel weapons to defeat urban targets and rapidly immobalize enemy combatants hiding in bunkers, caves, and basements requires new weapons and tactics. Thermobaric warheads can provide tailored blast response optimized for the defeat of these targets with low collateral damage. In this Phase I SBIR program, Powdermet will develop surface-coated metallic particles that can deliver tail ...

Rapid screening of chemical/biological threats and infectious diseases is a challenging task especially in remote locations due to the lack of appropriate laboratory infrastructure and advanced instrumentation. In such resource-scarce settings, wireless, robust, accurate, and easy-to-use diagnostics tools are required to enable real-time monitoring of various medical conditions, point-of-care appl ...

An advanced sensor for proximal detection of contaminants on surfaces is proposed based on hyperspectral differential polarization reflection of LWIR radiation from an active IR source, blackbody lamp or wavelength agile laser and an advanced unmixing algorithm whose feasibility was demonstrated by field test data in the Phase I program. The high signal-to-noise ratios provided by the active irrad ...

Raman spectroscopy is well suited for detecting trace surface contaminants that may indicate the presence of explosives, harmful chemical or biological agents, illicit drugs, or specific combinations of indicator chemicals used in processing nuclear materials. An example mobile Raman spectroscopy system is the vehicle mounted Joint Contaminated Surface Detector (JCSD), which uses a gaseous KrF exc ...

Purpose: Children who do not learn foundational mathematical concepts during elementary school generally get further behind in math as their math deficiencies compound over time. Through a prior IES SBIR Fast-Track award, the project team developed a series of supplemental math games designed to provide elementary students with engaging, adaptive, and personalized or team-based learning opportunit ...

Electronic waste (e-waste) is one of the most rapidly growing waste problems worldwide. Improper handling of e-waste results in vast amounts of toxic waste being sent to landfill and leaching into the water supply. Due to these concerns, e-waste recycling is a rapidly growing industry. Unfortunately, most current e-waste recycling processes rely on either manual hand sorting or differential densit ...

The environmental impact of wood coatings has become a pressing issue as the manufacturing of wooden products such as flooring, cabinetry, furniture and doors moves back to the United States amidst rising labor costs overseas. For 30 years, the bulk of these products have been painted in countries with lax environmental regulations, allowing the use of inexpensive but environmentally hazardous oil ...

SixPoint Materials will create low-cost, high-quality vertical gallium nitride (GaN) substrates using a multi-phase production approach that employs both hydride vapor phase epitaxy (HVPE) technology and ammonothermal growth techniques to lower costs and maintain crystal quality. Substrates are thin wafers of semiconducting material needed for power devices. In its two-phase project, SixPoint Mate ...

The overall goal of the SBIR Phase II program is development, fabrication, and demonstration of a fully integrated graphene-based sensor capable of detection of different types of chemical agents in the vapor phase with better than parts per billion (ppb) sensitivity and a high degree of specificity. It should also exhibit a reversible function of the sensing element. The program will synergistica ...