Award Data

To address the Chemical and Biological Defense programs (CBDs) need for medical countermeasures against mycotoxin intoxication, PhysicalOptics Corporation (POC) proposes to develop a new Mycotoxin Neutralization Treatment (MyNT). This proposed solution is based on neutralizingmycotoxin from its deleterious effects by acting on multiple levels of mycotoxin metabolism through the novel combination o ...

This project team will develop and test a prototype of Moby.Read, a stand-alone app for handheld devices or tablets. Using Moby.Read, grade school students will read a passage out loud and the speech-recognition software will generate an assessment of oral-reading fluency in real-time. The app is intended to replace face-to-face oral reading assessments done by teachers in order to save teachers t ...

This project team will develop and test a prototype an online platform to facilitate engineering project challenges within K–12 classrooms across many schools. The prototype will include a content management platform to enable a high volume of challenges for students to conduct projects on a broad range of STEM topics, such as computer coding, digital modeling, or producing simulations. In a pil ...

In prior research and development, the team and their partners developed EdSurge Concierge, an online platform to facilitate school improvement. With this Phase I funding, the project team will develop and test a next prototype of the platform with improved capability to generate information administrators need to make decisions on selecting technology tools to drive school improvement. The protot ...

Over 50 million Indian households cook on a bio-mass fire and have unreliable or no electricity but are anxious to purchase an affordable power stove which will provide on-demand power and lighting to their homes. Annually, projected sales of the power stove could save sixteen million trees, reduce cooking fire particulates by 90%, reduce the two million premature deaths caused from indoor air pol ...

Discharge of nutrients (e.g. phosphorus and ammonia) to surface waters can cause eutrophication and the formation of toxic algal blooms, threatening human health and the environment. However, current phosphorus treatment technologies such as chemical precipitation and conventional biological systems can be costly and ineffective to reliably achieve impending effluent regulatory limits of

Two major waste streams, thermoplastics and used automotive tires, need a technological and economic method to decrease their entry into our environment. Both have long life-cycles as waste, causing many deleterious environmental problems. The Phase I, II , and Ill goal is to divert plastic and tire waste and its pollution away from landfills and the environment into transformational new technolog ...

In this proposal, we aim to validate the human gut microbiome and arid soil as a source of antibiotic natural products (NPs ) by using ametagenomic NP discovery platform developed at Radiant Genomics. Recent studies suggest that the genomes of uncultivated microorganisms,like their cultivated counterparts, encode an enormous number of NPs. Gaining systematic access to NPs using standard, cultivati ...

Environmental DNA from three extreme samples will be isolated, cloned into a fosmid library (5760 clones) for sequencing. The sequencing datawill cover ~ 240 Megabases and will be assembled into contigs long enough (~ 40 Kilobases) to represent potential biosynthetic gene clusters(BGCs). This data will be compared to BGC databases looking for homology to antibiotic targets of DoD interest and with ...

To address CBDs need for development of analytical approaches to fuse sensor data from multiple modalities to provide common operationalpictures in threat environments, Physical Optics Corporation (POC) proposes to develop a Wavelet-based Approach for Signal Processing andAnalysis (WASP). WASP is based on novel application of wavelet-based analysis to multimodel, multidimensional data available fr ...