Award Data

Through this STTR contract, we propose to evaluate the efficacy of our vaccine, FlowVax Marburg, in nonhuman primates (NHPs). This will be achieved through four Tasks. In Task 1, we will manufacture the vaccine in a quantity sufficient for the animal studies. In Task 2, we will perform MHC genotyping on a representative population of NHPs and, based on results, select a set of MHC-matched NHPs for ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terrible morbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditional vaccines have contributed greatly to public health, they have some limitations especially in the context of operati ...

The performance of a composite material is heavily influenced by the strength and toughness of the interlaminar region, which is the resin rich area between the plies of a fiber reinforced composite.  The interlaminar region generally provides a direct path for crack propagation since no continuous reinforcement is present and is often the cause of failure in materials subjected to cyclic loadin ...

Carbonics, Inc. is the only small business entity that is razor-focused on developing and commercializing wafers-scale carbon nanotube (CNT) based RF products for mmWave communications that can outperform incumbent semiconductor high frequency technologies (GaAs & RF-CMOS). Our STTR Phase I accomplishments exceeded all expectations, setting a new world record for CNT FET RF technology (fT > 100 GH ...

Quantum information processing has the potential to revolutionize the U.S. economy, with a potential market value of hundreds of billions of dollars for quantum-information based technologies in a wide variety of sectors, including pharmaceuticals, energy, transportation, and cyber security. A major obstacle to realizing this potential is overcoming the error-prone nature of quantum information, w ...

There is a need to develop affordable and specific biosensors to defend against current and future biological threats. Biological methods of detection have been evolved by nature to detect molecules at the micro-scale with flexible specificity and with downstream effectors. Advances in cell-free technology allow for deployment of biosensors on pH-strip-type paper, an affordable, robust, disposable ...

A nondestructive test system is under development for thorough, rapid and economical evaluation of the structure and properties of polymer-inorganic interfaces during curing and in service. The system is capable of in-situ, real-time and spatially resolved monitoring of the molecular structure and properties. It employs (single-sided) NMR relaxometry principles to detect and quantify defects and d ...

Vadum proposes to mature its Vibration-Enhanced Underground Sensing (VENUS) technology into a reliable, shallow-buried low-metal-content landmine discrimination and classification solution with minimal False Alarm Rate (FAR).  VENUS exploits a novel vibration phenomenology to provide unique discriminatory information and estimated classification of the buried target that enhances and complements ...

A key goal stated in the United States Air Force Science and Technology Strategy for 2030 and Beyond is to “Increase the speed of battlespace understanding and decision-making to act faster than any adversary.” In this project, ISL and Ohio University (ISL-OU) will build on the success of Phase I and deliver a new game-changing capability for reliably performing complex radio frequency, multi- ...

OLGS is developing an automated tourniquet system. It is an intuitive device that works with the push of a button. The user only needs to know 'high-and-tight' and push the button for the tourniquet to be effective. It contains a band with wires embedded that is tightened by a motor-driven spool. It also contains a micro-controller unit with integrated sensors to ensure limb occlusion pressure is ...