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SBC: POLAR RAIN, INC. Topic: N/A
The video surveillance industry is experiencing dramatic change with the move from analog to digital video. Command centers need to have coordinated viewing of multiple camera feeds at one time, and the ability to switch automatically between feeds and display relevant patterns. Conventional security control rooms include a bank of monitors connected through a switch to an array of security camera ...STTR Phase I 2006 Department of Homeland Security
SBC: BROWN AND HERBRANSON IMAGING Topic: N/A
DESCRIPTION (provided by applicant): Broad long term objectives and specific aims: The long-term objective of this project is to develop a digital anatomical research resource library of very high-resolution computational models, and imaging data sets. Our objective is to produce an anatomical library otf the complete human skeleton. The implications of this project, both scientific and social are ...STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
SBC: AMERICAN LIFE SCIENCE PHARMACEUTICALS, INC. Topic: NINDS
Project Summary Traumatic brain injuryTBIcauses detrimental behavioral dysfunctions and brain neurodegeneration butunfortunatelythere currently is no effective pharmaceutical TBI treatmentThe underlying PhaseSTTR grant is to develop a new class of TBI drugs that inhibit the protease cathepsin BGenetically deleting the cathepsin B gene in mice results in substantial behavioral and pathology improve ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
SBC: IMMvention Therapeutix, Inc. Topic: NIAID
Summary Influenza virusa member of the orthomyxovirus familyhas three different types that infect humansABand CTypes A and B produce annual epidemicsand type A influenzawhich resides asymptomatically in birdscan cause pandemic infections in humansIn addition to common flu like symptomse gfeverchillsmalaisemuscle painin susceptible populations influenza can induce potentially fatal secondary compli ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
SBC: KOVOGEN Topic: N/A
DESCRIPTION (provided by applicant): The objective of this project is to develop a genetic test, involving the protein, RGS9, to identify patients that are at risk for developing tardive dyskinesia (TD) or L-DOPA induced dyskinesia (LID). Antipsychotic drugs have revolutionized the treatment of schizophrenia and psychotic disorders but a debilitating side-effect of "typical" antipsychotics is TD, ...STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
SBC: MAPP BIOPHARMACEUTICAL, INC. Topic: N/A
DESCRIPTION (provided by applicant): The central goal of this application is to develop a combination product comprising two fully human monoclonal antibodies (mAbs) produced in plants for the prevention of serious disease caused by respiratory syncytial virus (RSV). RSV causes high morbidity and mortality in certain neonate populations as well as in the elderly and in bone marrow transplant patie ...STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
SBC: SIGNATURE RESEARCH, INC. Topic: 1
Signature Research, Inc. (SGR) and Michigan Technological University (MTU) propose a Phase I STTR effort to develop a learning algorithm which exploits the spatio-spectral characteristics inherent within IR imagery and motion imagery.Our archive of modelled and labeled data sets will allow our team to thoroughly capture the variable elements that will drive machine learning performance.The overall ...STTR Phase I 2018 Department of DefenseNational Geospatial-Intelligence Agency
SBC: SERPLUS TECHNOLOGY LLC Topic: NIAID
PROJECT SUMMARY Asthma exacerbations are a major cause of ER visits and hospitalizations with annual direct costs of approximately $billionyear in the USAViral infectionsin particular rhinoviralRVinfectionsare a major precipitant of asthma exacerbations in allergic asthmaticsAs there are overRV serotypes andfor nowno RV vaccinenovel strategies to inhibit RV induced airway inflammation are needed t ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
SBC: ADELPHI TECHNOLOGY INC Topic: N/A
DESCRIPTION (provided by applicant): We propose to develop a commercial neutron source for the treatment of brain and liver cancer based on boron neutron capture therapy (BNCT). Boron-containing compounds are injected into a patient's bloodstream and accumulate in a malignant tumor. When irradiated with neutrons, the boron atoms preferentially capture neutrons and decay, releasing short-range radi ...STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
An innovative WGS platform for discovery, annotation, and interpretation of all forms of human genetic variation.SBC: Base2 Genomics LLC Topic: 172
PROJECT SUMMARY Modern DNA sequencing technologies have transformed our ability to interrogate human genomes in a single experimentthereby eliminating the inherent blind spots of gene panels and whole exome sequencingFurthermorerecent speed and economy improvements are driving the cost of whole genome sequencingWGSdown to that of WESthereforewe foresee a transition over the next two years to WGS a ...STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health