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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Developing Silicon Nanowire Sensors to Measuring Host-Cell Proteins at a Biomanufacturing Line

    SBC: Advanced Silicon Group            Topic: None

    Our biosensor is made of silicon nanowire arrays functionalized with antibodies to measure the concentration of specific proteins. In this grant we will take a sensor that has been demonstrated for use in measuring a set of generic host cell proteins and we will apply the sensor to measure a set of proteins for a specific cell line. In doing so, we will demonstrate the utility of our sensor to be ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  2. Direct Performance Evaluation of Additive Manufacturing Process Plans

    SBC: INTACT SOLUTIONS INC.            Topic: None

    Additive manufacturing is steadily advancing towards fulfilling its promise of customized and on-demand production of functional parts. However, performance of as-manufactured parts can differ significantly from the as-designed parts because the as-manufactured geometry differs from the as-designed geometry and the asmanufactured material properties are not known. Attempts to predict performance o ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  3. Developing a robust and scalable calibration approach to low-cost AQ sensing

    SBC: Aerodyne Research, Inc.            Topic: 813

    Poor air quality represents a major public health risk, contributing to an estimated one of every eight deaths worldwide. Low-cost air quality sensors have developed rapidly over the last few years and offer the opportunity to make air quality monitoring widespread at an affordable price. However, low-cost sensors are currently unable to deliver accurate, reliable data due to a lack of understandi ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  4. Development of a Rapid Monitoring System for Detection of Pathogens in Marine Aquaculture

    SBC: InnovaPrep, LLC            Topic: 836

    pathogens in marine aquaculture waters. Phase II research will look to improve sample concentration, cell lysis, and DNA purification techniques that were developed in Phase I. More specifically, optimization of the prototype lysis/elution fluid will be further developed for cell lysis using BSL-1 organisms, Vibrio harveyi, a surrogate for pathogenic Vibrio ssp. Techniques will be developed to ove ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  5. OpenORB Low-Cost Mooring Location Beacon for Costal Applications

    SBC: Triton Systems, Inc.            Topic: 825

    Triton Systems, Inc. proposes development of the Open-Source Oceanographic Asset Recovery Beacon (OpenORB) that will allow the deployment of coastal instrumentation moorings with affordable protection against loss. This open-source kit would significantly reduce the purchase price of a commercial location beacon by allowing the end-user to assemble a customized system with minimal time and effort. ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  6. Phase II Commercialization of HABStats: A Harmful Algal Bloom Species, Toxin and Total Phytoplankton Identification System

    SBC: CoastalOceanVision, Inc            Topic: 821

    In Phase I, we developed a prototype instrument for counting, sizing and identifying both non-toxic and toxic Harmful Algal Bloom (HAB) species. We did this by integrating three innovative technologies: High-throughput color, Light Field Imaging Flow Cytometry to acquire morphological information for each cell, Raman spectroscopy to acquire species-specific molecular information on pigments and tr ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  7. Measuring the Concentration of Host-cell Proteins in Biomanufacturing Using Silicon Nanowire Array Sensors

    SBC: Advanced Silicon Group            Topic: NA

    Our innovation is a low cost, sensitive, quantitative biosensor that can detect many biomarkers on the same chip. Our sensor consists of vertically aligned silicon nanowires. The silicon nanowires’ high surface area to volume ratio makes them sensitive to the environment around them and can thus lead to high sensitivity detection. Each of the nanowires can be functionalized to be sensitive to ei ...

    SBIR Phase I 2018 Department of CommerceNational Institute of Standards and Technology
  8. Riptide Hypoxic Zone AUV

    SBC: Riptide Autonomous Solutions, LLC            Topic: 827

    TECHNICAL ABSTRACT: Buoyancy driven oceanographic gliders, although reasonably cost effective, have challenges operating in the zones due to high gradients in water density. Under this topic, Riptide will provide a cost-effective autonomous undersea vehicle (AUV) design leveraged from Riptide's family of man-portable AUVs that can more effectively map the hypoxic areas. The stated goals of this to ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  9. Harmful Algal Bloom Species, Toxin and Total Phytoplankton Identification System (HABStats) for HandHeld, Remotely Networked or Submersible Operation

    SBC: CoastalOceanVision, Inc            Topic: 821

    TECHNICAL ABSTRACT: We propose to develop and commercialize the next generation of low cost, low power, ruggedized, and accurate phytoplankton single cell and whole colony counting, characterization and classification system called HABStats. We will accomplish this using the following three unique and innovative approaches: 1) High-throughput color, Light Field Imaging Flow Cytometry to acquire mo ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  10. Low-cost Mooring Location Beacon for Coastal Applications

    SBC: Triton Systems, Inc.            Topic: 825

    TECHNICAL ABSTRACT: Triton Systems, Inc. proposes development of the Open-Source Oceanographic Asset Recovery Beacon (OpenORB) that will allow the deployment of coastal instrumentation moorings with affordable protection against loss. This open-source kit would significantly reduce the purchase price of a commercial location beacon by allowing the end-user to assemble a customized system with mini ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration

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