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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Multimodal Acoustic Tool for Inline Pipe Inspection

    SBC: CREARE LLC            Topic: 180PH1

    A Multimodal Acoustic Tool for Inline Pipe Inspection 3/19/2018 The US energy transport pipeline system is a longstanding distribution network with most of its still standing pipes being installed between the 1950s–1970s. Due to degradation mechanisms, such as embrittlement, capable of causing a two-fold reduction in fracture toughness, pipe rupture is a major risk. Current nondestructive ins ...

    SBIR Phase I 2018 Department of Transportation
  2. Rapid Assessment of Air Void System in Fresh Concrete

    SBC: CREARE LLC            Topic: 171FH2

    Proposal title: Rapid Assessment of Air Void System in Fresh Concrete Water expansion during freeze-thaw cycles can cause deterioration in concrete, leading to scaling, cracking, and crumbling over a period of years. Resistance to this damage is achieved with a system of voids formed by adding surfactants to the fresh concrete to stabilize air bubbles naturally entrained during mixing. The volume ...

    SBIR Phase II 2018 Department of Transportation
  3. Broken Rail Detection from Flashing Rear End Device

    SBC: CREARE LLC            Topic: 171FR2

    Proposal title: Broken Rail Detection from Flashing Rear End Device Broken rails are a common cause of mainline derailments and a particular concern given the increasing use of our rail system for passenger traffic and petroleum products. The progressive nature of the defects provides an opportunity for early detection of cracks before they become significant enough to cause a derailment. Unfortu ...

    SBIR Phase II 2018 Department of Transportation
  4. A Thermal Distillation Process for Expanding Water Resources

    SBC: AIL Research, Inc            Topic: 84

    Most of the world's freshwater usage--as high as 70%--goes to agriculture. Unfortunately, in many of the country's major farming regions secure sources of agriculture water are threatened: freshwater aquifers are being over pumped, coastal saltwater intrusion is tainting freshwater supplies, agricultural run-off is dumping nitrates into the environment, and severe droughts are periodically ...

    SBIR Phase I 2018 Department of Agriculture
  5. Mill Development Model Development and Testing

    SBC: Innovative Natural Resource Solutions, LLC            Topic: 86

    INRS and MDP will collaborate to build an analytical model that demonstrates the probability of success - and opportunities for enhancement - for the redevelopment of idled industrial assets. This model will be developed and refined using the former pulp and paper mill in Old Town, ME., and data supplied by multiple redevelopment efforts elsewhere in the State of Maine. Based upon learnings and ex ...

    SBIR Phase I 2018 Department of Agriculture
  6. GreenCare Interactive Guide for Knee Replacement Surgery

    SBC: PEER Technologies PLLC            Topic: NIA

    Project SummaryAbstract The goal of this Phase I work is to finish development of an innovative interactive app designed to help patients appropriately use total knee replacementTKRsurgery and provide support to achieve best outcomesTKR is highly effective for treating advanced osteoarthritis of the kneebut it has risksAppropriate use can be assured by engaging patients in a Shared Decision Making ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. Activating latent growth factors for cartilage regeneration


    Project summary Articular cartilage lesions are prevalent disorders affecting millions of AmericansDeprived of spontaneous healing capacitycartilage lesions may further deteriorate and lead to the onset of osteoarthritisOAOA represents a leading cause of chronic disabilities in the U Sand ultimately warrants total joint arthroplastyA common aspiration in orthopedic medicine is to regenerate the da ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Adaptable Pediatric Neurocognitive Assessment

    SBC: CREARE LLC            Topic: 103

    PROJECT SUMMARY ABSTRACTMillions of children around the globe are afflicted with conditions that can alter neuropsychological developmentincluding human immunodeficiency virusHIVtraumatic brain injuryTBIcerebral malariaand a host of other developmental and acquired diseases and disordersEarly assessment and intervention are critical in overcoming cognitive and developmental deficiencies and are in ...

    SBIR Phase II 2018 Department of Health and Human Services
  9. Restoring Beta-lactam efficacy against methicillin-resistant Staphylococci

    SBC: Prokaryotics, Inc.            Topic: NIAID

    Methicillin resistant Staphylococcus aureusMRSAand methicillin resistant Staphylococcus epidermidisMRSEare a major cause of bloodstream infections in the hospital and in the communityIndeedMRSA remains the second leading cause of mortality by drug resistant bacterial pathogens in the USAAlthough two mechanistically novel antibiotic classes exist to treat such infectionsDaptomycinDAP and LinezolidL ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. Preparation and development of a stabilized C3 analog for the treatment of paroxysmal nocturnal hemoglobinemia

    SBC: Cascade Biotechnology            Topic: NHLBI

    Abstract We propose to develop analogs of human complement Cthat have the ability to form a stable CconvertaseIn additionthese proteins will be designed to decrease the affinity of the proteins for factor H bindingAll proteins will be expressed in the Baculovirus insect protein expression systemand tested for their ability to form a stable Cconvertase enzyme that is able to deplete complement in h ...

    SBIR Phase I 2018 Department of Health and Human Services

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