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SBC: EnergyEne Inc. Topic: ST18C001
Opportunity: Guayule, a US native plant, is the only alternate rubber crop with an established, mechanized, agronomic system. Problem: Low rubber yields and lack of effective resin and bagasse coproduct valorization, have prevented widespread adoption by American farmers and processors. Rubber is only made when the cytoplasmic monomer pool (isopentenyl-pyrophosphate; IPP) is larger than that requi ...STTR Phase I 2019 Department of DefenseDefense Advanced Research Projects Agency
Genetically Engineered Pancreatic Organoids Composed of Extracellular Matrix Hydrogels for the Purpose of Long-Term Therapeutic Glycemic MaintenanceSBC: ECMedical LLC Topic: ST18C004
Glucose abnormalities significantly affect patient morbidity and mortality. Currently, glycemic control is achieved via medications and exogenous insulin regimens that are costly both in terms of qualified personnel and consumables. Furthermore, none of these approaches are curative. Strategies under development such artificial pancreases do not necessarily address these limitations because they w ...STTR Phase I 2019 Department of DefenseDefense Advanced Research Projects Agency
SBC: CFD RESEARCH CORPORATION Topic: DHA19A001
Traumatic injuries account for 30% of all life years lost in the US and is the leading cause of death for people under 46 years of age. Uncontrolled bleeding or hemorrhage constitute 30-40% of trauma related deaths and are considered to be a major cause oSTTR Phase I 2019 Department of DefenseDefense Health Agency
SBC: CORNERSTONE RESEARCH GROUP INC Topic: DHP16C003
Cornerstone Research Group (CRG) and the University of Texas (UT) will team to develop a fast and accurate automated analysis program for USV scoring. This automated tool will enable greater research efficiency and throughput allowing greater strides in developing treatments for post-traumatic stress disorder through rodent-based research. Building off prior work by UT on a first generation auto-s ...STTR Phase I 2017 Department of DefenseDefense Health Agency
SBC: Design Interactive, Inc Topic: DHA17A003
Design Interactive Inc. (DI) and Eastern Virginia Medical School (EVMS) propose to develop an Augmented reality Learning Environment for Refresher Training (ALERT) that provides realistic and relevant Tactical Combat Casualty Care (TC3) scenarios using AR technologies integrated with mannequins for pre-deployment training and humans for deployed training environments. ALERT will facilitate learnin ...STTR Phase I 2017 Department of DefenseDefense Health Agency
SBC: ARCHIE MD INC. Topic: DHA17A002
Providing Army combat medics with meaningful experience in treatment of battlefield injuries is a particular challenge. Moulage has the potential to assist in acquiring what could otherwise be very hard-to-come-by preparatory experience for the distressing real-life emergencies medics and soldiers may encounter in the field. However, current approaches to moulage are limited in their ability to re ...STTR Phase I 2017 Department of DefenseDefense Health Agency
SBC: NOKOMIS INC Topic: DHP16C005
This proposal is dedicated to development of portable device for -on site- diagnostic of burn injury. The design will utilize a technology Ultra-Wide Band RF waves of ultra-low intensity (harmless by Federal Standards). The emitted RF waves will reflect from boundaries between tissues normal and damaged by injury to quantitatively characterize severity of burn and would require minimal skills fro ...STTR Phase I 2017 Department of DefenseDefense Health Agency
SBC: NOKOMIS INC Topic: DHP16C002
Nokomis proposes to develop a real-time microwave spectroscopy device to identify Volatile Organic Compounds (VOCs) associated with Pulmonary Oxygen Toxicity. Exhaled breath contains VOCs that act as signatures of bodily health, and are able to be utilized for health diagnostics. The proposed work will demonstrate sensitivity to the presence of chemicals at less than 50 ppb concentration levels, a ...STTR Phase I 2017 Department of DefenseDefense Health Agency
SBC: CHI SYSTEMS INC Topic: DHA17A003
CHI Systems, in partnership with the Virginia Serious Games Institute, proposes to design, develop, and assess the Interactive Mixed Media augmented Reality Simulation Engine (IMMERSE) technology, a compelling and instructionally rich training experience using augmented and mixed-reality for TC3 trainees, and then evaluate the impact of the IMMERSE approach on trainee understanding and training ef ...STTR Phase I 2017 Department of DefenseDefense Health Agency
SBC: SWITCHBOX INC Topic: DHA18B001
Most standard-of-care tools and techniques for evaluating neck disorders are subjective, unreliable, and do not provide actionable information for providers, payers, and organizations to deliver efficient and effective care. This lack of objective neck heSTTR Phase I 2019 Department of DefenseDefense Health Agency