Award Data

This Small Business Technology Transfer (STTR) Phase I project proposes to combine a novel metabolically engineered Chinese hamster ovary (CHO) cell line with a unique, high performance, continuous cell-culture bioreactor to demonstrate the commercial viability of producing a bioengineered heparin from CHO cells. This CHO cell line overexpresses critical enzymes in the heparin biosynthesis pathway ...

This Small Business Technology Transfer (STTR) Phase I project proposes to develop a simulation and design software for droplet-based microfluidic devices. Designing microfluidic platforms for biological and biochemistry applications is a laborious process involving several experimental trials. Scaling up a basic design to a parallelized device is another challenge. As a result, computational tool ...

This Small Business Technology Transfer Phase I project is titled ?Performance Optimization Toolbox for Wave Energy Conversion Devices?. Advanced wave prediction and concurrent online adjustment of the operating parameters (such as hydraulic system pressure and generator load) of existing wave energy conversion (WEC) devices have the potential to increase their power extraction efficiency by at le ...

This Small Business Technology Transfer Research (STTR) Phase I project aims to develop quantitative models of wind variability to aid the design of reliable, low-carbon electric grid systems with high wind penetration. All abundant renewable resources are naturally variable, creating a challenge for their integra¬tion onto an ?always on? electric grid. While this variability challenge is now beg ...

This Small Business Innovation Research (SBIR) Phase I project is aimed at demonstrating commercial viability for a new self-healing corrosion-protection system. Corrosion significantly impacts both the costs and availability of commercial aircraft, costing tens of billions of dollars annually. The proposed Self-Healing Anti-Corrosion Coating (SHAC) is capable of repeatable repair and sustained pr ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will be to have a transformative impact on time-correlated imaging applications in a variety of fields, including quantum information science, biomedical imaging, and remote sensing, by offering order-of-magnitude improvements in dark count rates and time resolution over comparably sized photo ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to develop a widely applicable, innovative pipeline for drug discovery against rare genetic disorders. While each orphan disease affects a small fraction of individuals, thousands exist, affecting 400 million people world-wide. The challenge to bring therapies to the clinics for diseases th ...

This SBIR Phase I project aims to focus on the challenges neuroradiologists and neurosurgeons experience when visualizing complex brain aneurysms. Brain aneurysms, which occur in 2-3% of the population, are balloon-like dilations of a blood vessel supplying the brain which may rupture and result in severe headaches, paralysis, coma and death. Currently, radiologists viewing Magnetic Resonance Imag ...

The broader impact/commercial potential of this STTR project is to chemically recycle carbon dioxide, which would otherwise be released to the atmosphere, to useful fuels and products thus providing a closed loop for production and emissions for many common products. Virtually every industry uses petroleum and/or natural gas, either through transportation or plastics (e.g., packaging), and there i ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is to create transparency around the business logic used by stakeholders in the healthcare system to make transactional decisions as well as create alignment around the current status of healthcare transactions that are part of the work in process. To most people who interact with the healthcare syste ...