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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10103

    Current drug discovery and development programs are severely limited by the expensive animal trials and oversimplified in vitro models. Results obtained from the in vitro models are not predictive of in vivo toxicity owing to significant difference in testing from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device for quantitati ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  2. Microfluidic High-throughput Platform for Determining of Kinetic Constants of Enzyme Variants

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10107

    Molecular biology techniques allow generating combinatorial libraries of large number of enzyme variants. However, there is currently no technology available for screening the enzyme libraries for identifying variants with improved activity for the substrate. We propose to develop a novel, microfluidic, high-throughput platform for determining kinetic constants of enzyme variants and identifying v ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  3. AC Impedance Sensor for Collective Protection Filter Residual Life Indicator

    SBC: GUILD ASSOCIATES INC            Topic: CBD10106

    Guild Associates, Inc. proposes to develop and evaluate an active electrochemical sensor based residual life indicator (RLI) for adsorptive carbon filters. The sensing system of the RLI will operate by analyzing the electrochemical state of the carbon within the filter and evaluate the remaining adsorptive reactive capacities of the filter. The sensor design will be challenged against an array of ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  4. In vitro Models Suitable for High-throughput Screening of Drug Toxicities in Human Tissues

    SBC: Nico Technologies Corp.            Topic: CBD10103

    The drug R&D cycle is long and very expensive. In many ways, this status quo can no longer be sustained. One of the reasons for such great cost is that the vast majority of drug candidates are screened out at the stages of animal and human trials. More efficient methods of testing of drugs at the stage of ex-vivo studies, which are substantially less expensive than animal and human testing cyc ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  5. Micro Weather Sensor (MWS)

    SBC: UES INC            Topic: SOCOM10006

    The Special Operations Forces mission requirement for remote weather sensing can be satisfied with an innovative solution that addresses tactical mobility in high threat environments. Within this context UES proposes the development of a novel Micro Weather Sensor, a modular system consisting of a comprehensive sensor suite and a compact, powerful networking device. The suite measures temperatur ...

    SBIR Phase I 2010 Department of DefenseSpecial Operations Command
  6. High Speed Combatant Craft Automated Ride Control

    SBC: MARINE1 LLC            Topic: SOCOM10005

    Marine 1, LLC and senior business partner Moxahela Enterprises, LLC are pleased to present this proposal for the US Special Operations Command (USSOCOM) Small Business Innovative Research (SBIR) topic number SOCOM10-005 for high speed combatant craft automated ride control. USSOCOM has identified the need for a lightweight, automated ride control system that will model and predict craft motion to ...

    SBIR Phase I 2010 Department of DefenseSpecial Operations Command
  7. Clean, Green, ChemBio Defense/Fire Retardant Process Using Nanotechnology

    SBC: Aqua Resources Corporation            Topic: SOCOM10007

    The dynamics of nano-size interactions of metal hydroxide nanoplatelets is a new field of material science. Initial research conducted by Aqua Resources and the Department of Defense, offers the promise of an innovative means of effectively defending against Chemical/Biological (CB) warfare agents in a cost effective manner without the attendant residues and long-term damage associated with tradit ...

    SBIR Phase I 2010 Department of DefenseSpecial Operations Command
  8. Micro Combat ID (MID)

    SBC: GLOBAL MILITARY EXPERT CONSULTING AND INSTRUCTION, LLC            Topic: SOCOM10008

    GMECI proposes to combine existing commercial template matching and feature extraction algorithms with existing military EOIR sensor technology, to automatically highlight in real time friendly forces on existing displays. The proposed technology, Blue force Designated Optical Templates (BlueDOTs) will allow automatic computer recognition and highlighting to discern among individual, customized lo ...

    SBIR Phase I 2010 Department of DefenseSpecial Operations Command
  9. An automated, high throughput, resin-free device for large scale protein purification

    SBC: CFD RESEARCH CORPORATION            Topic: CBD12102

    Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  10. A Novel, Aerodynamics-augmented Continuous Ionization System for Electrostatic Collection of Bioaerosols

    SBC: CFD RESEARCH CORPORATION            Topic: CBD12107

    Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these issues, we propose to develop and demonstrate a novel bioaerosol ionization and collection ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
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