Award Data

Guild Associates, Inc. proposes to develop and evaluate an active electrochemical sensor based residual life indicator (RLI) for adsorptive carbon filters. The sensing system of the RLI will operate by analyzing the electrochemical state of the carbon within the filter and evaluate the remaining adsorptive reactive capacities of the filter. The sensor design will be challenged against an array of ...

Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...

Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these issues, we propose to develop and demonstrate a novel bioaerosol ionization and collection ...

Current drug discovery and development programs are severely limited by the expensive animal trials and oversimplified in vitro models. Results obtained from the in vitro models are not predictive of in vivo toxicity owing to significant difference in testing from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device for quantitati ...

DRS Scientific proposes a new type of Acousto-Optic Tuned Filter (AOTF) polarimetric hyperspectral imager that is compact, rugged, and inexpensive, has no moving parts, is free of optical aberrations, and is fast and sensitive. It will cover 8-12 mm with 8 cm-1 spectral resolution or finer, and will have mFlick sensitivity with a cooled camera, and

PCP Ammunition Company will research the design and development of Lightweight .50 caliber precision ammunition under this SBIR Phase I contract. PCP will concentrate our efforts on several separate criteria in order to improve upon the current .50 caliber round by utilizing PCP"s current lightweight polymer .50 caliber case. First, we will compare the performance of the current round agains ...

The dynamics of nano-size interactions of metal hydroxide nanoplatelets is a new field of material science. Initial research conducted by Aqua Resources and the Department of Defense, offers the promise of an innovative means of effectively defending against Chemical/Biological (CB) warfare agents in a cost effective manner without the attendant residues and long-term damage associated with tradit ...

Elevated levels of human butyrylcholinesterase (BuChE) confer protection from chemical warfare nerve agents and other organophosphorous chemicals. As a prophylactic, the key to enabling this protection is the ability to maintain elevated concentrations of BuChE in the plasma for days or weeks. Thus far, plasma-derived and PEGylated recombinant forms of BuChE have been tested in humans. However, ...

Given the benefits of exercise on general health, orally active compounds that can mimic or potentiate the effects of exercise have been of keen interest as therapeutic and dietary ingredients. Our proposed approach for enhancement of USSOCOM Multi-Purpose Canine (MPC) endurance and sensory performance using an exercise mimetic is based on the observation that age-related decline of nicotinamide ...

PCP Ammunition Company will deliver a family of Lightweight Advanced Polymer Sub-Sonic Ammunition. We will do this by adapting our current family of calibers by decreasing the internal volume and shape of the case to match the optimal performance requirements of the cartridges. This will result in a sub-sonic ammunition that is lightweight, clean burning (due to the internal volume and dimension ...