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SBC: Vova Ida, LLC Topic: 999
SUMMARYParkinsonandapos s diseasePDis the second most prevalent neurodegenerative disorder after Alzheimerandapos s diseaseADaffecting more thanmillion people in the United StatesBecause age is the major risk factorthe prevalence of both diseases is steadily increasing as our population agesPD belongs to the group of protein misfolding neurodegenerative diseases that are due to the misfolding and ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
Metal Digital Direct Manufacturing (MDDM) for Close-Out of Combustion Chambers and Nozzle FabricationsSBC: Keystone Synergistic Enterprises, LLC Topic: T12
This NASA sponsored STTR project will investigate methods for close-out of large, liquid rocket engine, nickel or stainless steel nozzle, coolant channels utilizing robotic laser and pulsed-arc additive manufacturing (AM)methods. Structural jacket to coolant channel land area interface strength will be quantified and metallurgical characterization completed.Process optimizations will be conducted ...STTR Phase II 2019 National Aeronautics and Space Administration
SBC: VOXTEL, INC. Topic: T9
To address the urgent need for 3D flash-lidar technology for landing on solar system bodies and for spacecraft rendezvous and docking with satellites, an effort is proposed to fabricate, characterize, and test a versatile, high-sensitivity InGaAs APD 3D flash lidar and to advance the technology-readiness level (TRL) of lidar technologies suitable for NASA mission requirements. Leveraging an existi ...STTR Phase II 2019 National Aeronautics and Space Administration
SBC: Simulated Inanimate Models LLC Topic: 103
Project SummarySimulation training is unique in its ability for repetitive practice of a wide variety of scenarios and to reflect on performance without jeopardizing a patient s safetySurgical skills simulators have been successful in bridging gaps of the current training modelhoweverthese simulators fall short of offering a complete operative experienceOperative exposure with live patients still ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
Adaptive Markov Inference Game Optimization (AMIGO) for Rapid Discovery of Evasive Satellite BehaviorsSBC: INTELLIGENT FUSION TECHNOLOGY, INC. Topic: AF17CT02
Space superiority requires space protection and space situational awareness (SSA), which rely on rapid and accurate space object behavioral and operational intent discovery. The presence of adversaries in addition to real-time and hidden information constraints greatly complicates the decision-making process in controlling both ground-based and space-based Air Force surveillance assets. The focus ...STTR Phase II 2019 Department of DefenseAir Force
SBC: N5 SENSORS INC Topic: T6
N5 Sensors partnering with George Mason University (GMU) have demonstrated ultra-small, low-power gas sensors, ideally suited for integrated space suit monitoring. A single-chip carbon dioxide (CO2), oxygen (O2), and ammonia (NH3) sensors capable of operating at high-humidity conditions, different range of oxygen in the environment and with low-power consumption was demonstrated as a proof-of-conc ...STTR Phase II 2019 National Aeronautics and Space Administration
The Daily Progress System- A Recovery Support Tool to Reduce Health Disparities in Outpatient Substance Use TreatmentSBC: COG ANALYTICS, LLC Topic: 102
ABSTRACTSubstance use disordersSUDsincluding opioid use disorderscontinue to be one of the most serious public health issues in the USleading to negative physical and mental health problemsfamily disruptionand premature deathAfrican Americans with drug use histories that are under criminal justice supervision are particularly vulnerable to experiencing the negative consequences associated with SUD ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
Novel Home-Based and Low-Cost ECG Device for periodic evaluation of the presence of atrial fibrillationSBC: Global Instrumentation, LLC Topic: 600
Abstract Atrial fibrillation (AF) prevalence is estimated to 1% of the general population in the United States. A shocking 30% to 60% (according to studies) of patients with AF are unaware of their diagnosis (silent AF). Most AF patients will suffer from congestive heart failure or/and develop thromboembolic events leading to a dramatic reduction of patients’ quality of life, and a significant c ...STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: LYST THERAPEUTICS LLC Topic: NHLBI
SUMMARY Despite significant advances in the surgical and medical management of congenital heart diseasecongenital cardiac anomalies remain a leading cause of death in the newborn periodMost severe forms of congenital heart disease require multiplestaged surgical interventionsA significant source of the heightened morbidity and mortality associated with these operations is the development of cardia ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: KLEIN BUENDEL, INC. Topic: 102
Project Summary While studies support the efficacy of comprehensiveschool wide interventions in reducing bullyingthese types of programs can require significant time and financial resources for implementationresulting in barriers to providing school based bullying preventionespecially in low income and rural communitiesAdditionallyalthough training bystanders to act asdefenderson behalf of targets ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health