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Host-Targeted Antiviral Drugs Providing Rapid, Scalable, Stable, Broad-Spectrum MedicalCountermeasure Against Marburg VirusSBC: EVRYS BIO LLC Topic: CBD18A002
In a pandemic or exposure to weaponized Marburg virus the morbidity, mortality and social unrest that will ensue before vaccines orMilitary operating on foreign soil as well as to the population of the US Homeland. Practically all threat agents of biological origin (except forcertain non-proteinaceous toxins, typically produced by marine organisms and fungi) have their structure and vital function ...STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
SBC: CFD RESEARCH CORPORATION Topic: CBD18A001
In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
SBC: PATHOVACS INCORPORATED Topic: CBD18A001
The focus of this STTR phase I component is on proof-of-concept studies demonstrating applicability of technical approaches for identificationof circulatory diagnostic markers for infectious disease. Therefore, the primary objective of this project is to determine feasibility of one suchtechnical approach called Proteomics-based Expression Library Screening (PELS), for identification of pathogen-d ...STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
SBC: Faraday Technology, Inc. Topic: MDA18T003
This proposed STTR program addresses the challenge of developing advanced absorptive baffles to minimize stray and reflected light across the visible and infrared wavebands for exo-atmospheric optical sensors and seeker telescopes. To achieve this goal Faraday Technology and Pacific Northwest National Laboratory will develop electrochemically textured pyramidal surfaces with CNT black coatings as ...STTR Phase I 2019 Department of DefenseMissile Defense Agency
SBC: MRL MATERIALS RESOURCES LLC Topic: MDA17T001
Metallic additive manufacturing (AM) is an attractive technology for the production of lethality test articles due to the potential for significantly reduced lead time and manufacturing cost.However, in order to be effective in providing accurate lethality data, the properties of the AM material have to match closely the properties of conventionally manufactured alloys found in real threat targets ...STTR Phase I 2018 Department of DefenseMissile Defense Agency
SBC: Plasma Processes, LLC Topic: MDA09T002
Hypersonic missile defense systems are being designed to reach global threats. During flight, external surfaces are predicted to reach temperatures in excess of 2200C. As a result, innovative, high performance thermal protection systems (TPS) are of great demand. Among ultra-high temperature ceramics (UHTC), it is well known that ZrB2- and HfB2-based materials have high melting temperatures and ...STTR Phase I 2010 Department of DefenseMissile Defense Agency
Development for Radiation Hardened Applications of Advanced Electronics Materials, Processes, and DevicesSBC: RNET TECHNOLOGIES INC Topic: MDA09T006
The Missile Defense Agency (MDA) seeks technical investigations related to the development and application of advanced electronic materials, processes, and devices to meet its need for radiation hardened, high performance electronics for critical space and missile applications. With the advent of smaller transistor dimensions and reductions in price per bit, significant changes in materials and pr ...STTR Phase I 2010 Department of DefenseMissile Defense Agency
SBC: Sinmat Inc Topic: MDA09T001
Gallium Nitride (GaN) substrates are ideal materials for fabrication of high-power and high-frequency devices based on III-V materials. The current state-of-the-art Chemical Mechanical Polishing (CMP) methods are plagued by several challenges, including, surface charge affects due to surface contamination, and sub-surface damages, which can limit the quality of III-V devices. Furthermore, there is ...STTR Phase I 2010 Department of DefenseMissile Defense Agency
SBC: DGNSS Solutions, LLC Topic: MDA09T003
The primary objective of the proposed research is to develop proof of concept of a software programmable X-Band radar system using low cost antenna array technology with digital beamforming architecture based on multiple receiver channels. The performance objectives will aim at a minimum of 400 MHz instantaneous bandwidth and a minimum instantaneous dynamic range of 52 dB. The objective of the t ...STTR Phase I 2010 Department of DefenseMissile Defense Agency
SBC: Terves LLC Topic: MDA17T004
Magnesium alloys have 35% lower density compared to aluminum, with improved temperature stability compared to high strength aluminum.They can also be fabricated with minimum gauge thicknesses considerably thinner than fiber composites, and are weldable, with much higher impact resistance.Traditional magnesium alloys, however, have had lower strengths than more developed aluminum alloys.Powder meta ...STTR Phase I 2018 Department of DefenseMissile Defense Agency